1826-18-2 Usage
Description
Thiazole, 5-methyl-4-phenylis a heterocyclic aromatic compound that features a thiazole ring with a methyl group and a phenyl group substituent. It is widely recognized for its diverse range of biological activities, such as antimicrobial, antiviral, and anticancer properties, and is a key component in the synthesis of drugs, dyes, pigments, and other organic compounds within the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
Thiazole, 5-methyl-4-phenylis utilized as a key intermediate in the synthesis of various drugs, leveraging its unique structure and biological activities to contribute to the development of new therapeutic agents.
Used in Antimicrobial Applications:
This chemical compound serves as an antimicrobial agent, effectively combating a range of microbial infections due to its inherent properties.
Used in Antiviral Applications:
Thiazole, 5-methyl-4-phenylis employed as an antiviral agent, helping to inhibit the replication and spread of viruses, thereby providing a potential treatment option for viral infections.
Used in Anticancer Applications:
It is used as an anticancer agent, where its biological activities contribute to the inhibition of tumor growth and the progression of cancer, offering a potential therapeutic approach for cancer treatment.
Used in Dye and Pigment Production:
Thiazole, 5-methyl-4-phenylis used as an intermediate in the production of dyes and pigments, capitalizing on its chemical structure to create a variety of colorants for different industries.
Used in Neurological Disorder Treatment:
Thiazole, 5-methyl-4-phenylhas been studied for its potential role in the treatment of neurological disorders, suggesting that it may have therapeutic benefits in managing such conditions.
Used in Drug Development:
As a building block for the development of new drugs, Thiazole, 5-methyl-4-phenylplays a crucial role in the creation of pharmaceuticals with specific therapeutic benefits, contributing to advancements in medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 1826-18-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,2 and 6 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1826-18:
(6*1)+(5*8)+(4*2)+(3*6)+(2*1)+(1*8)=82
82 % 10 = 2
So 1826-18-2 is a valid CAS Registry Number.
1826-18-2Relevant articles and documents
Novel series of 3-amino-N-(4-aryl-1,1-dioxothian-4-yl)butanamides as potent and selective dipeptidyl peptidase IV inhibitors
Nitta, Aiko,Fujii, Hideaki,Sakami, Satoshi,Satoh, Mikiya,Nakaki, Junko,Satoh, Shiho,Kumagai, Hiroki,Kawai, Hideki
, p. 7036 - 7040 (2013/01/15)
A series of novel 3-amino-N-(4-aryl-1,1-dioxothian-4-yl)butanamides were investigated as dipeptidyl peptidase IV (DPP-4) inhibitors. Introduction of a 4-phenylthiazol-2-yl group showed highly potent DPP-4 inhibitory activity. Among various derivatives, (3R)-3-amino-N-(4-(4-phenylthiazol-2-yl)-tetrahydro-2H- thiopyran-4-yl)-4-(2,4,5-trifluorophenyl)butanamide 1,1-dioxide (30) reduced blood glucose excursion in an oral glucose tolerance test by oral administration.
