18272-07-6

Basic information

• Product Name: 1-(4-hydroxy-4-phenylpiperidin-1-yl)-2-(1H-indol-3-yl)ethane-1,2-dione
• CAS NO: 18272-07-6
• Molecular Formula: C₂₁H₂₀N₂O₃
• Molecular Weight: 348.3951
• Mol File: 18272-07-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 593.4°C at 760 mmHg
• Flash Point: 312.7°C
• Density: 1.338g/cm³
• Vapor Pressure: 6.27E-15mmHg at 25°C
• Refractive Index: 1.685
• CAS DataBase Reference: 1-(4-hydroxy-4-phenylpiperidin-1-yl)-2-(1H-indol-3-yl)ethane-1,2-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-hydroxy-4-phenylpiperidin-1-yl)-2-(1H-indol-3-yl)ethane-1,2-dione(18272-07-6)
• EPA Substance Registry System: 1-(4-hydroxy-4-phenylpiperidin-1-yl)-2-(1H-indol-3-yl)ethane-1,2-dione(18272-07-6)

Safety Data

• Hazardous Substances Data: 18272-07-6(Hazardous Substances Data)

Upstream product

• 40807-61-2 4-hydroxy-4-phenylpiperidin 
• 22980-09-2 indolyl-3-glyoxylyl chloride 

Downstream Products

• 18272-20-3 1-(2-(Indol-3-yl)ethyl)-4-hydroxy-4-phenylpiperidine 

Relevant articles and documents

Syntesis and Cardiovascular Activity of Piperidyl Ethyl Indoles

Some new 2-substituted-N-(substituted piperidyl) indol-3-yl-glyoxylamides and 2-substituted-3-ethyl> indoles have been synthesized as possible cardiovascular agents by the condensation of different piperidines with indole glyoxylylchloride followed by reduction with lithium aluminium hydride in anhydrous dimethoxyethane.