183070-41-9

Basic information

• Product Name: (S)-Benzyl 2-(benzyloxycarbonylamino)-3-(4-(trifluoromethylsulfonyloxy)phenyl)propanoate
• Synonyms: (S)-Benzyl 2-(benzyloxycarbonylamino)-3-(4-(trifluoromethylsulfonyloxy)phenyl)propanoate;Cbz-L-Tyrosine benzyl ester triflate;(S)-Benzyl 2-(((benzyloxy)carbonyl)aMino)-3-(4-hydroxyphenyl)propanoate trifluoroMethanesulfonate;(S)-Benzyl 2-(((benzyloxy)carbonyl)amino)-3-(4-hydroxy-phenyl)propanoate trifluoromethanesulfonat;(S)-Benzyl 2-(((benzyloxy)carbonyl)amino)-3-(4-hydroxy-phenyl)propanoate trifluoromethanesulfo
• CAS NO: 183070-41-9
• Molecular Formula: C₂₅H₂₂F₃NO₇S
• Molecular Weight: 537.5048896
• Mol File: 183070-41-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (S)-Benzyl 2-(benzyloxycarbonylamino)-3-(4-(trifluoromethylsulfonyloxy)phenyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-Benzyl 2-(benzyloxycarbonylamino)-3-(4-(trifluoromethylsulfonyloxy)phenyl)propanoate(183070-41-9)
• EPA Substance Registry System: (S)-Benzyl 2-(benzyloxycarbonylamino)-3-(4-(trifluoromethylsulfonyloxy)phenyl)propanoate(183070-41-9)

Safety Data

• Hazardous Substances Data: 183070-41-9(Hazardous Substances Data)

Usage

General Description

"(S)-Benzyl 2-(benzyloxycarbonylamino)-3-(4-(trifluoromethylsulfonyloxy)phenyl)propanoate" is a complex organic chemical compound possessing several functional groups including sulfone, benzyloxycarbonyl, and ester groups. The benzyl group is a common phenyl group attached to a CH2, and the benzyloxycarbonylamino refers to the carboxamide group linked to a benzyl group. The trifluoromethylsulfonyloxy group contains fluorine, sulfur and oxygen atoms, which could lend the molecule possible biological activity. As a derivative of propanoic acid, it also contains a carboxylate ester at its terminal. However, without more information, the specific properties, reactivity, and applications of this compound are not clear.

Upstream product

• 37595-74-7 N,N-phenylbistrifluoromethane-sulfonimide 
• 5513-40-6 benzyl N-carbobenzyloxy-L-tyrosine 
• 42406-77-9 L-tyrosine benzyl ester 
• 100-39-0 benzyl bromide 
• 1164-16-5 Z-L-Tyr-OH 
• 100-51-6 benzyl alcohol 
• 60-18-4 L-tyrosine 
• 358-23-6 trifluoromethylsulfonic anhydride 

Downstream Products

• 214491-30-2 N-benzyloxycarbonyl-4-(2,3-dimethyl-2,3-butanediolatoboryl)-L-phenylalanine benzyl ester 
• 257628-06-1 Cbz-Tyr(Tf)-Bzl 
• 257628-05-0 Cbz-Tyr(Tf)-Bzl 
• 1415357-60-6 C₃₃H₄₀NO₈P 
• 183070-44-2 (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(tert-butoxycarbonyl)phenyl)propanoic acid 
• 183070-42-0 4-((S)-2-Benzyloxycarbonyl-2-benzyloxycarbonylamino-ethyl)-benzoic acid 
• 185553-37-1 3-{4-[(S)-2-Carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)-ethyl]-phenyl}-3-oxo-2-(triphenyl-λ⁵-phosphanylidene)-propionic acid tert-butyl ester 
• 185553-38-2 3-{4-[(S)-2-Carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)-ethyl]-phenyl}-3-oxo-2-(triphenyl-λ⁵-phosphanylidene)-propionic acid ethyl ester 
• 185553-39-3 3-[4-((S)-2-Benzyloxycarbonyl-2-benzyloxycarbonylamino-ethyl)-phenyl]-3-oxo-2-(triphenyl-λ⁵-phosphanylidene)-propionic acid tert-butyl ester 
• 185553-40-6 3-[4-((S)-2-Benzyloxycarbonyl-2-benzyloxycarbonylamino-ethyl)-phenyl]-3-oxo-2-(triphenyl-λ⁵-phosphanylidene)-propionic acid ethyl ester 
• 183070-43-1 4-((S)-2-Benzyloxycarbonyl-2-benzyloxycarbonylamino-ethyl)-benzoic acid tert-butyl ester 
• 473259-95-9 (S)-2-amino-3-(4-(methoxycarbonyl)phenyl)propanoic acid 
• 866114-96-7 benzyl (S)-2-[(benzyloxycarbonyl)amino]-3-[4-(borono)phenyl]propionate 
• 164203-33-2 N-benzyloxycarbonyl-4-borono-L-phenylalanine 

Relevant articles and documents

A concise synthesis of enantiomerically pure L-(4-Boronophenyl)alanine from L-tyrosine

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Synthesis of novel L-phenylalanine derivatives substituted with a keto ylide as stable precursor of a vicinal tricarbonyl moiety

Novel L-phenylalanine derivatives 5 containing a vicinal tricarbonyl moiety at the para position of the phenyl ring were prepared in 4 steps starting from N(α)-Cbz-L-tyrosine benzyl ester. A 7 step reaction sequence lead to N(α)-Fmoc protected derivatives 9 with the tricarbonyl structure masked as its stable keto ylide precursor, which is suitable for solid phase peptide synthesis. The phosphoranylidene intermediates 8 were transformed to the trioxo compounds 5 with Oxone as oxidant.