183205-18-7Relevant articles and documents
Cancerous metastasis inhibitors containing uracil derivatives
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, (2008/06/13)
This invention provides a drug which has inhibitory activities against thymidine phosphorylase and inhibits metastasis of a cancer. Specifically, this invention relates to a cancerous metastasis inhibitor comprising, as an active ingredient, a uracil derivative represented by the following formula (1): wherein R1represents a chlorine, bromine or iodine atom or a cyano or lower alkyl group and R2represents a substituted or unsubstituted 4-8 membered hetero-cyclic group having nitrogen atoms or a substituted or unsubstituted amidinothio, guanidino, (lower alkyl)amidino, amino or like group, or a salt thereof.