1849251-81-5

Basic information

• Product Name: 3-bromo-1-(2,2-difluoroethyl)-1H-pyrazole
• CAS NO: 1849251-81-5
• Molecular Weight: 211.009
• Mol File: 1849251-81-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-bromo-1-(2,2-difluoroethyl)-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-bromo-1-(2,2-difluoroethyl)-1H-pyrazole(1849251-81-5)
• EPA Substance Registry System: 3-bromo-1-(2,2-difluoroethyl)-1H-pyrazole(1849251-81-5)

Safety Data

• Hazardous Substances Data: 1849251-81-5(Hazardous Substances Data)

Upstream product

• 598-39-0 1,1-difluoro-2-iodoethane 
• 14521-80-3 3-bromo-1H-pyrazole 

Relevant articles and documents

ATAZANAVIR (ATV) ANALOGUES FOR TREATING HIV INFECTIONS

The invention provides a compound of Formula I: or a pharmaceutically acceptable salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of Formula I, processes for preparing compounds of Formula I, the compound of formula (I) for use in therapeutic methods for treating the proliferation of the HIV virus, treating AIDS or delaying the onset of AIDS symptoms in a mammal using compounds of Formula I. Preferred compounds are N-[(2S) -1-[2-[(2S,3S)-2-hydroxy-3-[[(2S)-2-(methoxycarbonylamino) -3,3-dimethylbutanoyl]amino]-4-phenylbutyl]-2-[(phenyl) methyl]hydrazinyl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate atazanavir (ATV) analogues substituted by several heterocycles, such as e.g. pyrazole (Rl); e.g. oxetane (substituent of X2); e.g. pyridine or pyrimidine (X1); e.g. piperazine or 3,8-diazabicyclo[3.2.1]octan (X2).