185815-56-9 Usage
Description
2,4-Dicyano-3-(2-Methylpropyl)-pentanediaMide is an organic compound that serves as an impurity in Pregabalin, a GABA analogue used for various medical applications. It is characterized by its unique molecular structure, which includes a pentanediaMide backbone with a 2-methylpropyl group and two cyano groups at the 2,4 positions.
Uses
Used in Pharmaceutical Industry:
2,4-Dicyano-3-(2-Methylpropyl)-pentanediaMide is used as an impurity in the production of Pregabalin, which is a GABA analogue. Pregabalin is utilized as an anticonvulsant for the treatment of various conditions such as epilepsy, neuropathic pain, and generalized anxiety disorder. The presence of this impurity in Pregabalin may affect the drug's efficacy and safety, making it crucial to monitor and control its levels during the manufacturing process.
As an impurity in Pregabalin, 2,4-Dicyano-3-(2-Methylpropyl)-pentanediaMide may also be indirectly involved in other applications where Pregabalin is used, such as in the treatment of fibromyalgia, diabetic neuropathy, and other related conditions. However, its specific role and impact in these applications would depend on the concentration and interaction of the impurity with the active pharmaceutical ingredient, Pregabalin.
Check Digit Verification of cas no
The CAS Registry Mumber 185815-56-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,5,8,1 and 5 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 185815-56:
(8*1)+(7*8)+(6*5)+(5*8)+(4*1)+(3*5)+(2*5)+(1*6)=169
169 % 10 = 9
So 185815-56-9 is a valid CAS Registry Number.
185815-56-9Relevant articles and documents
Preparation method and application of high-purity dimethyl 3-isobutylglutarate
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Paragraph 0124; 0126; 0133-0134; 0171-0172, (2019/12/02)
The invention provides a preparation method and application of high-purity dimethyl 3-isobutylglutarate. Specifically, the invention provides the method for preparing dimethyl 3-isobutylglutarate shown as a formula 2, and the method comprises the step of enabling 3-isobutylglutaric acid to react in methanol in the presence of potassium permanganate and concentrated sulfuric acid, so as to obtain the high-purity dimethyl 3-isobutylglutarate. The method is simple, easy to control, high in product conversion rate, mild in reaction condition, convenient for industrial production and low in cost, the product is easy to purify, and the purity is up to 99% or above.
