186246-68-4

Basic information

• Product Name: 7-hydroxy-3-(4-acetoxyphenyl)-4H-chromen-4-one
• Synonyms: 7-hydroxy-3-(4-acetoxyphenyl)-4H-chromen-4-one
• CAS NO: 186246-68-4
• Molecular Weight: 296.279
• Mol File: 186246-68-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 7-hydroxy-3-(4-acetoxyphenyl)-4H-chromen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-hydroxy-3-(4-acetoxyphenyl)-4H-chromen-4-one(186246-68-4)
• EPA Substance Registry System: 7-hydroxy-3-(4-acetoxyphenyl)-4H-chromen-4-one(186246-68-4)

Safety Data

• Hazardous Substances Data: 186246-68-4(Hazardous Substances Data)

Upstream product

• 3682-01-7 daidzein diacetate 
• 486-66-8 daidzein 

Downstream Products

• 38482-80-3 Daidzein O₇-glucuronide 
• 188881-57-4 7-(6-bromohexyloxy)-3-(4-hydroxyphenyl)-4H-chromen-4-one 

Relevant articles and documents

Syntheses of daidzein-7-yl β-D-glucopyranosiduronic acid and daidzein-4′,7-yl di-β-D-glucopyranosiduronic acid

Syntheses of the title compounds - commonly known as 'daidzein 7-glucuronide' and 'daidzein 4′,7-diglucuronide' - are described. Selective 7-deacetylation of 4′,7-di-O-acetyldaidzein is employed.

Nickel-catalyzed methylation of aryl halides/tosylates with methyl tosylate

This work describes the cross-electrophile methylation of aryl bromides and aryl tosylates with methyl tosylate. The mild reaction conditions allow effective methylation of a wide set of heteroaryl electrophiles and dimethylation of dibromoarenes.

Facile synthesis of flavonoid 7-O-glycosides

Highly regioselective removal of the 7-O-acyl groups of the peracylated flavones, isoflavones, and flavonols (PhSH, imidazole, NMP) followed by effective glycosylation with glycosyl trifluoroacetimidates (BF 3·Et2O) and cautious deprotection of the acyl groups under basic conditions afforded the desired 7-O-flavonoid glycosides in satisfactory yields.