186347-28-4 Usage
Explanation
The molecular formula represents the number of atoms of each element present in a molecule of the compound.
Explanation
The compound is derived from piperidine, a six-membered nitrogen-containing ring, and has specific functional groups attached to it.
Explanation
The BOC group is a common protecting group used in organic synthesis to protect amines from unwanted reactions.
Explanation
The cyano group is a carbon-nitrogen triple bond (C≡N) that acts as a functional group in the compound.
Explanation
A 2-methylphenyl group is a phenyl ring (C6H5) with a methyl group (CH3) attached to the second carbon atom.
Explanation
The compound is used as a building block or intermediate in the synthesis of more complex organic molecules.
Explanation
Due to its unique structure and properties, the compound is utilized in the development and synthesis of drugs and agrochemicals.
Explanation
The compound's structure makes it a valuable tool in the design and synthesis of novel therapeutic agents for various medical applications.
Explanation
The compound is likely to dissolve in organic solvents such as dichloromethane, ethyl acetate, or acetone, which is common for many organic compounds.
Explanation
The compound is expected to be stable at room temperature and in the absence of strong acids, bases, or oxidizing agents.
Chemical Structure
Piperidine derivative with a BOC protecting group, a cyano group, and a 2-methylphenyl substituent
BOC Protecting Group
tert-butoxycarbonyl
Cyano Group
CN
2-Methylphenyl Substituent
ortho-tolyl
Application
Intermediate in organic synthesis
Use in Pharmaceutical and Agrochemical Industries
Preparation of various pharmaceuticals and agrochemicals
Field of Medicinal Chemistry
Development of new drugs and therapeutic agents
Solubility
Soluble in organic solvents
Stability
Stable under normal conditions
Check Digit Verification of cas no
The CAS Registry Mumber 186347-28-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,6,3,4 and 7 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 186347-28:
(8*1)+(7*8)+(6*6)+(5*3)+(4*4)+(3*7)+(2*2)+(1*8)=164
164 % 10 = 4
So 186347-28-4 is a valid CAS Registry Number.
186347-28-4Relevant articles and documents
SUBSTITUTED PIPERIDINES THAT INCREASE p53 ACTIVITY AND THE USES THEREOF
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Page/Page column 156, (2011/05/05)
The present invention provides a compound of Formula (1) as described herein or a pharmaceutically acceptable salt, solvate or ester thereof. The compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and methods of treating cancer using the same.
Cyclic imides as potent and selective α-1A adrenergic receptor antagonists
DiPardo, Robert M.,Patane, Michael A.,Newton, Randall C.,Price, RoseAnn,Broten, Theodore P.,Chang, Raymond S.L.,Ransom, Richard W.,Di Salvo, Jerry,Freidinger, Roger M.,Bock, Mark G
, p. 1959 - 1962 (2007/10/03)
We disclose a new compound class of potent and selective α-1A adrenergic receptor antagonists exemplified by the geminally, disubstituted cyclic imide 7. The optimization of lead compounds resulting in the cyclic imide motif is highlighted. The results of in vitro and in vivo studies of selected compounds are presented.
ALPHA 1A ADRENERGIC RECEPTOR ANTAGONISTS
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, (2008/06/13)
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