187266-45-1Relevant articles and documents
Enantioselective synthesis of the lactone moiety of HMG-CoA reductase inhibitor: Stereoselective synthesis of (+)-(4R,6R)-4-hydroxy-6-(2-phenylethyl)-tetrahydro-2H-pyran-2-one
Honda, Toshio,Ono, Satoko,Mizutani, Hirotake,Hallinan, Keith O.
, p. 181 - 184 (2007/10/03)
The enantioselective synthesis of the lactone moiety of (+)-compactin and (+)-mevinolin was established starting from a meso-3,5-dihydroxycyclohexanone derivative by employing an enantioselective deprotonation strategy.