18739-99-6

Basic information

• Product Name: cinnamyl 4-tolyl thioether
• Synonyms: cinnamyl 4-tolyl thioether
• CAS NO: 18739-99-6
• Molecular Weight: 240.369
• Mol File: 18739-99-6.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: cinnamyl 4-tolyl thioether(CAS DataBase Reference)
• NIST Chemistry Reference: cinnamyl 4-tolyl thioether(18739-99-6)
• EPA Substance Registry System: cinnamyl 4-tolyl thioether(18739-99-6)

Safety Data

• Hazardous Substances Data: 18739-99-6(Hazardous Substances Data)

Upstream product

• 106-38-7 para-bromotoluene 
• 104-54-1 3-Phenylpropenol 
• 106-45-6 para-thiocresol 
• 444575-79-5 carbonic acid 1,1-dimethylethyl 1-phenyl-2-propenyl ester 
• 2327-99-3 1-phenylpropadiene 
• 103-19-5 di(p-tolyl) disulfide 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 
• 4192-77-2 ethyl cinnamate 
• 4392-24-9 3-bromo-1-phenyl-1-propenyl bromide 

Downstream Products

• 20605-48-5 (E)-1-cinnamylsulfonyl-4-methylbenzene 
• 16215-11-5 trans-cinnamyl p-tolyl sulfone 
• 1421914-12-6 (E)-8-(4-phenylbuta-1,3-dien-1-ylidene)-1,4-dioxaspiro[4.5]decane 
• 62158-92-3 (2,2,2-trifluoroethyl) (4-methylphenyl) sulfide 

Relevant articles and documents

Hemin Catalyzed Dealkylative Intercepted [2, 3]-Sigmatropic Rearrangement Reactions of Sulfonium Ylides with 2, 2, 2-Trifluorodiazoethane

A dealkylative intercepted [2, 3]-sigmatropic rearrangement reaction of allylic sulfides with 2, 2, 2-trifluorodiazoethane (CF3CHN2) is reported, the commercially available and biocompatible catalyst hemin was found to efficiently catalyze this transformation across a diverse set of allylic sulfides with in situ generated CF3CHN2, providing excellent yields (up to 99%) under mild condition without inert gas protection. In addition, CF3CHN2 exhibited unique reactivity toward this process compared with other frequently used diazo reagents. This work expands the range of carbene-mediated transformations catalyzed by hemin and introduces a concise and general strategy for exploiting new possibility of reactions concerning organosulfides. (Figure presented.).

Ruthenium-catalyzed decarboxylative C-S cross-coupling of carbonothioate: synthesis of allyl(aryl)sulfide

A novel ruthenium-catalyzed decarboxylative cross-coupling of carbonothioate is disclosed. This method provides straightforward access to the corresponding allyl(aryl)sulfide derivatives in generally good to excellent yields under mild conditions and feat

One-Pot Copper-Catalysed Thioetherification of Aryl Halides Using Alcohols and Lawesson's Reagent in Diglyme

A new protocol for the thioetherification of structurally varied alcohols with aryl halides using Lawesson's reagent, catalysed by copper(I) iodide, and using diglyme as a safe solvent was developed. Using this method, the reactions of aryl halides proceeded efficiently, and the desired sulfides were obtained in high to excellent yields. The method uses alcohols as starting materials, which is a significant advantage over methods that start from thiols. Alcohols are widely commercially available in a much greater structural diversity than thiols, and they are also nontoxic and not foul-smelling. A reaction mechanism was proposed. A copper-catalysed method for the thioetherification of alcohols with aryl halides using Lawesson's reagent was developed.