18780-68-2

Basic information

• Product Name: Carbonic acid, 4-(chlorocarbonyl)-2,6-dimethoxyphenyl ethyl ester
• Synonyms: 3.5-Dimethoxy-4-aethoxycarbonyloxy-benzoylchlorid;3.5-Dimethoxy-4-aethoxycabonyloxy-benzoylchlorid;3,5-dimethoxy-4-ethoxycarbonyloxybenzoyl chloride;4-Aethoxycarbonyloxy-3,5-dimethoxy-benzoylchlorid;4-ethoxycarbonyloxy-3,5-dimethoxy-benzoyl chloride;Carbaethoxysyringoyl-chlorid
• CAS NO: 18780-68-2
• Molecular Formula: C12H13ClO6
• Molecular Weight: 288.685
• Mol File: 18780-68-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 74-75 °C
• Boiling Point: 416.2±45.0 °C(Predicted)
• Density: 1.286±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Carbonic acid, 4-(chlorocarbonyl)-2,6-dimethoxyphenyl ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbonic acid, 4-(chlorocarbonyl)-2,6-dimethoxyphenyl ethyl ester(18780-68-2)
• EPA Substance Registry System: Carbonic acid, 4-(chlorocarbonyl)-2,6-dimethoxyphenyl ethyl ester(18780-68-2)

Safety Data

• Hazardous Substances Data: 18780-68-2(Hazardous Substances Data)

Upstream product

• 118-41-2 Eudesmic acid 
• 530-57-4 3,5-dimethoxy-4-hydroxybenzoic acid 
• 18780-67-1 4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoic acid 

Downstream Products

• 118952-80-0 4-ethoxycarbonyloxy-3,5-dimethoxy-benzoic acid-(3-pyrrolidino-propyl ester) 
• 122765-11-1 4-ethoxycarbonyloxy-3,5-dimethoxy-benzoic acid-(3-pyrrolidino-propylamide) 
• 84-36-6 syrosingopine 
• 50916-10-4 2-(4-ethoxycarbonyloxy-3,5-dimethoxy-benzoyl)-[1,2]oxazinane 
• 50916-05-7 3,4,5-Alkoxybenzamid 
• 95704-96-4 10-(4-ethoxycarbonyloxy-3,5-dimethoxy-benzoyl)-10H-phenothiazine 
• 95958-65-9 2-chloro-10-(4-ethoxycarbonyloxy-3,5-dimethoxy-benzoyl)-10H-phenothiazine 
• 7046-90-4 2-Chlor-10-<2-(4-ethoxycarbonyloxy-3,5-dimethoxy-benzoyloxy)-ethyl>-phenothiazin 
• 7046-91-5 2-Trifluormethyl-10-<2-(4-ethoxycarbonyloxy-3,5-dimethoxy-benzoyloxy)-ethyl>-phenothiazin 
• 18780-70-6 Leonuramin 
• 24697-74-3 Leonurine 
• 24735-18-0 3,5-dimethoxy-4-hydroxybenzoic acid [4-guanidino]-1-butyl ester hydrochloride 
• 18780-69-3 4-ethoxycarbonyl-oxy-3,5-dimethoxy-benzoic acid (4-phthalimido)butyl ester 
• 133668-62-9 N-[3-(3,5-dimethoxy-4-hydroxybenzoylamino)propyl]-N'-[3-(3,4,5-trimethoxybenzoylamino)propyl]homopiperazine 

Relevant articles and documents

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Six-step synthesis of Leonurine and toxicity study on zebrafish

Leonurine (1), an important ingredient in leonurus sibiricus L., can be used for some gynecological disease. We have developed a concise and efficient synthetic route of Leonurine, which can be optimized for mass production. Commercially available compound 6 and 2,3-dihydrofuran (7) were used as starting materials. And the toxicity study on zebrafish shows that Leonurine would promote the hatching of zebrafish embryos at low concentration and result in acute death or chronic lethal toxicity at high concentration.