18809-63-7

Basic information

• Product Name: 2-diphenylmethylamino-ethanol
• Synonyms: 2-diphenylmethylamino-ethanol
• CAS NO: 18809-63-7
• Molecular Weight: 227.306
• Mol File: 18809-63-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-diphenylmethylamino-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-diphenylmethylamino-ethanol(18809-63-7)
• EPA Substance Registry System: 2-diphenylmethylamino-ethanol(18809-63-7)

Safety Data

• Hazardous Substances Data: 18809-63-7(Hazardous Substances Data)

Upstream product

• 141-43-5 ethanolamine 
• 90-99-3 diphenylchloromethane 
• 776-74-9 Bromodiphenylmethane 
• 1013-88-3 Benzophenone imine 
• 93818-03-2 N-Benzhydryl-oxamidsaeure-aethylester 
• 817168-45-9 2-(benzhydrylamino)-2-oxoacetic acid 
• 80500-07-8 2-(diphenylmethyleneamino)ethanol 

Downstream Products

• 1588488-75-8 C₁₇H₁₈N₂O 
• 1588489-02-4 C₂₅H₂₇NO 
• 1588488-89-4 C₁₈H₂₂NO⁽¹⁺⁾*CF₃O₃S^(1-) 
• 1588488-87-2 C₂₀H₂₄NO₂⁽¹⁺⁾*CF₃O₃S^(1-) 
• 1588488-85-0 C₂₅H₂₈NO⁽¹⁺⁾*CF₃O₃S^(1-) 
• 1588488-76-9 C₁₇H₁₇ClN₂ 
• 1256092-64-4 4-(2-(benzhydrylamino)ethoxy)butan-2-one 
• 103269-57-4 1-(benzhydryl-benzoyl-amino)-2-benzoyloxy-ethane 

Relevant articles and documents

Syntheses of morpholine-2,3-diones and 2-hydroxymorpholin-3-ones: Intermediates in the synthesis of aprepitant

The preparation of morpholine-2,3-diones and 2-hydroxymorpholin-3-ones from N-substituted β-amino alcohols is reported. These were useful intermediates in the synthesis and development of aprepitant.

Skin care

PROBLEM TO BE SOLVED: To provide a skin care preparation suitable for a cosmetic (provided that quasi drugs are included) or the like, for detail, a skin care preparation having whitening effects, particularly preventive or improving effects against pigme

Preparation of N-arylmethyl aziridine derivatives, 1,4,7,10-tetraazacyclododecane derivatives obtained therefrom and N-arylmethyl-ethanol-amine sulphonate esters as intermediates

PCT No. PCT/GB96/00552 Sec. 371 Date Dec. 2, 1997 Sec. 102(e) Date Dec. 2, 1997 PCT Filed Mar. 8, 1996 PCT Pub. No. WO96/28420 PCT Pub. Date Sep. 19, 1996Aziridines may be subjected to a cyclooligomerization reaction to produce polyazacycloalkane compounds useful for example in the preparation of chelating agents for use in diagnostic imaging contrast agents. N-benzyl-aziridine in particular is useful as it can be cyclotetramerized and debenzylated to yield cyclen, a key intermediate in chelating agent preparation. The invention provides a particularly attractive route to production of N-benzyl and other N-arylmethyl aziridines of formula (I) where each R1 is independently hydrogen or a group AR and Ar is an optionally substituted phenyl group. The process comprises reacting a purified N-arylmethylethanolaminesulphonate ester with a base. N-arylmethyl-ethanolamine sulphonate ester of the formula R'NHCH2CH2OSO3H, wherein the N-arylmethyl group R' is an N-(bisarylmethyl) or N-(triarylmethyl) group, as intermediates. In a further aspect, the invention provides compounds of formula (II) where Ar and R1 are as hereinabove defined and at least two differing ArCHR21 moieties are present.