188940-43-4

Basic information

• Product Name: [5-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-4-(3-methoxy-phenylsulfanyl)-isoxazol-3-yl]-carbamic acid tert-butyl ester
• Synonyms: [5-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-4-(3-methoxy-phenylsulfanyl)-isoxazol-3-yl]-carbamic acid tert-butyl ester
• CAS NO: 188940-43-4
• Molecular Weight: 494.728
• Mol File: 188940-43-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [5-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-4-(3-methoxy-phenylsulfanyl)-isoxazol-3-yl]-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [5-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-4-(3-methoxy-phenylsulfanyl)-isoxazol-3-yl]-carbamic acid tert-butyl ester(188940-43-4)
• EPA Substance Registry System: [5-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-4-(3-methoxy-phenylsulfanyl)-isoxazol-3-yl]-carbamic acid tert-butyl ester(188940-43-4)

Safety Data

• Hazardous Substances Data: 188940-43-4(Hazardous Substances Data)

Upstream product

• 188940-62-7 5-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-isoxazole-3-carboxylic acid 
• 188940-61-6 5-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-isoxazole-3-carboxylic acid ethyl ester 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 61362-77-4 5-[tert-butyldimethylsilyloxy]pent-1-yne 
• 15570-12-4 3-methoxybenzenethiol 
• 5390-04-5 pent-1-yn-5-ol 
• 59014-89-0 bis(3-methoxyphenyl)disulfide 
• 174078-93-4 {5-[3-(tert-Butyl-dimethyl-silanyloxy)-propyl]-isoxazol-3-yl}-carbamic acid tert-butyl ester 

Downstream Products

• 302957-80-8 4-[3-(4-tert-butyl-benzenesulfonylamino)-4-(3-methoxy-phenylsulfanyl)-isoxazol-5-yl]-butyric acid 
• 302957-81-9 4-[3-(4-tert-butyl-benzenesulfonylamino)-4-(3-methoxy-phenylsulfanyl)-isoxazol-5-yl]-butyric acid methyl ester 
• 188940-50-3 4-tert-butyl-N-[5-(3-cyano-propyl)-4-(3-methoxy-phenylsulfanyl)-isoxazol-3-yl]-benzenesulfonamide 
• 188940-48-9 4-tert-butyl-N-[5-(3-hydroxy-propyl)-4-(3-methoxy-phenylsulfanyl)-isoxazol-3-yl]-benzenesulfonamide 
• 188940-39-8 4-tert-butyl-N-[4-(3-methoxy-phenylsulfanyl)-5-(4-oxo-butyl)-isoxazol-3-yl]-benzenesulfonamide 
• 188940-45-6 acetic acid 3-[3-tert-butoxycarbonylamino-4-(3-methoxy-phenylsulfanyl)-isoxazol-5-yl]-propyl ester 
• 188940-46-7 acetic acid 3-[3-amino-4-(3-methoxy-phenylsulfanyl)-isoxazol-5-yl]-propyl ester 
• 188940-44-5 [5-(3-hydroxy-propyl)-4-(3-methoxy-phenylsulfanyl)-isoxazol-3-yl]-carbamic acid tert-butyl ester 

Relevant articles and documents

Discovery and synthesis of a potent sulfonamide ET(B) selective antagonist

The synthesis and structure-activity relationships of a series of sulfonamide endothelin antagonists are described. In the course of our modification studies, we discovered ET(B) selective antagonists. The most potent compound 15f displays IC50 values of 1.7 μM and 0.002 μM to ET(A) and ET(B) receptors, respectively. (C) 2000 Elsevier Science Ltd. All rights reserved.