189065-49-4 Usage
General Description
4-(3-(trifluoromethyl)phenyl)morpholine, also known as TFMPM, is a chemical compound with the molecular formula C11H12F3NO. It is a heterocyclic organic compound containing a morpholine ring and a trifluoromethylphenyl group. TFMPM is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals due to its medicinal properties and biological activity. It is also used as a ligand in catalytic reactions and as a reagent in organic synthesis. TFMPM is a white to off-white crystalline solid with a melting point of 42-45°C and a boiling point of 300°C. It is considered a potentially hazardous substance and should be handled and stored with care.
Check Digit Verification of cas no
The CAS Registry Mumber 189065-49-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,9,0,6 and 5 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 189065-49:
(8*1)+(7*8)+(6*9)+(5*0)+(4*6)+(3*5)+(2*4)+(1*9)=174
174 % 10 = 4
So 189065-49-4 is a valid CAS Registry Number.
189065-49-4Relevant articles and documents
Cobalt-Catalyzed Electrophilic Amination of Aryl- and Heteroarylzinc Pivalates with N-Hydroxylamine Benzoates
Chen, Yi-Hung,Gra?l, Simon,Knochel, Paul
, p. 1108 - 1111 (2018)
Aryl- and heteroarylzinc pivalates can be aminated with O-benzoylhydroxylamines at 25 °C within 2–4 h in the presence of 2.5–5.0 % CoCl2?2 LiCl to furnish the corresponding tertiary arylated or heteroarylated amines in good yields. This electrophilic amination also provides access to diarylamines and aryl(heteroaryl)amines. A new tuberculosis drug candidate (Q203) was prepared in six steps and 56 % overall yield by using this cobalt-catalyzed amination as the key step.
ARALKYL AND ARALKYLIDENE HETEROCYCLIC LACTAMS AND IMIDES
-
Page/Page column 53, (2008/06/13)
The present invention relates to compounds of the formula (I) wherein R1, R2, R3, X, Y and the dashed line are defined in the specification, to intermediates for their preparation, to pharmaceutical compositions containing them and to their medicinal use as psychotherapeutic agents.
