1892-22-4 Usage
Description
3-amino-2-Piperidinone, also known as 3-Aminopiperidin-2-one, is a slightly pale yellow to yellow crystalline or powdery chemical compound. It is characterized by its unique chemical structure, which includes a piperidinone ring with an amino group at the 3-position. 3-amino-2-Piperidinone has garnered interest due to its potential applications in various fields, particularly in the medical and pharmaceutical industries.
Uses
Used in Diagnostic Applications:
3-amino-2-Piperidinone is used as a biomarker for the detection and diagnosis of the silent phase of Alzheimer's disease. Its presence in biological samples can indicate the early stages of the disease, allowing for timely intervention and potentially slowing the progression of cognitive decline.
Used in Pharmaceutical Industry:
3-amino-2-Piperidinone is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical structure makes it a valuable building block for the development of new drugs, particularly those targeting the central nervous system.
Used in Chemical Research:
Due to its unique properties, 3-amino-2-Piperidinone is also used in chemical research as a starting material for the synthesis of various organic compounds. Its reactivity and structural features make it an attractive candidate for further exploration and development in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1892-22-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,9 and 2 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1892-22:
(6*1)+(5*8)+(4*9)+(3*2)+(2*2)+(1*2)=94
94 % 10 = 4
So 1892-22-4 is a valid CAS Registry Number.
InChI:InChI=1/C5H10N2O/c6-4-2-1-3-7-5(4)8/h4H,1-3,6H2,(H,7,8)/t4-/m1/s1
1892-22-4Relevant articles and documents
PROTAC-mediated crosstalk between E3 ligases
Steinebach, Christian,Kehm, Hannes,Lindner, Stefanie,Vu, Lan Phuong,K?pff, Simon,López Mármol, álvaro,Weiler, Corinna,Wagner, Karl G.,Reichenzeller, Michaela,Kr?nke, Jan,Gütschow, Michael
supporting information, p. 1821 - 1824 (2019/02/12)
Small-molecule heterobifunctional degraders can effectively control protein levels and are useful research tools. We assembled proteolysis targeting chimeras (PROTACs) from a cereblon (CRBN) and a von-Hippel-Lindau (VHL) ligase ligand and demonstrated a PROTAC-induced heterodimerization of the two E3 ligases leading to unidirectional and efficient degradation of CRBN.
NITROGEN-CONTAINING HETEROCYCLIC COMPOUND
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Paragraph 0748, (2013/03/26)
The present invention provides a novel compound having a superior activity as an ERR-alpha modulator and useful as an agent for the prophylaxis or treatment of ERR-alpha associated diseases. The present invention relates to a compound represented by the formula (1) wherein each symbol is as defined in the specification, or a salt thereof
QUINAZOLINE DERIVATIVES
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Page/Page column 129, (2008/06/13)
A quinazoline derivative of the formula (I) wherein: R1, R2, R3, R3a, R4, R5, R5a R6, R7, a, m and p are as defined in the description. Also claimed are pharmaceutical compositions containing the quinazoline derivative, the use of the quinazoline derivatives as medicaments and processes for the preparation of the quinazoline derivative. The quinazoline derivatives of formula (I), are useful in the treatment of hyperproliferative disorders such as a cancer.
