190724-36-8

Basic information

• Product Name: Benzyl-((1S,2R)-2-hydroxy-1-methyl-2-phenyl-ethyl)-carbamic acid ethyl ester
• Synonyms: Benzyl-((1S,2R)-2-hydroxy-1-methyl-2-phenyl-ethyl)-carbamic acid ethyl ester
• CAS NO: 190724-36-8
• Molecular Weight: 313.397
• Mol File: 190724-36-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzyl-((1S,2R)-2-hydroxy-1-methyl-2-phenyl-ethyl)-carbamic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzyl-((1S,2R)-2-hydroxy-1-methyl-2-phenyl-ethyl)-carbamic acid ethyl ester(190724-36-8)
• EPA Substance Registry System: Benzyl-((1S,2R)-2-hydroxy-1-methyl-2-phenyl-ethyl)-carbamic acid ethyl ester(190724-36-8)

Safety Data

• Hazardous Substances Data: 190724-36-8(Hazardous Substances Data)

Upstream product

• 61347-76-0 NH-benzyl-(1R,2S)-norephedrine 
• 541-41-3 chloroformic acid ethyl ester 
• 3198-15-0 (1R,2S)-(-)-norephedrine hydrochloride 
• 100-52-7 benzaldehyde 

Downstream Products

• 190724-40-4 (4S,5S)-3-Benzyl-4-methyl-5-phenyl-oxazolidin-2-one 
• 61347-73-7 (1S,2S)-2-(benzylamino)-1-phenyl-1-propanol 

Relevant articles and documents

Preparation of 2-oxazolidinones by intramolecular nucleophilic substitution

Treatment of N-alkoxycarbonyl, N-benzyl protected β-amino alcohols with triphenylphosphine and hexachloroethane in 1,2-dichloroethane induces cyclization to 2-oxazolidinones, which are formed by intramolecular attack with inversion of configuration at the secondary alcohol. In contrast, mono N-substituted alkyl carbamates undergo chlorination under the same conditions.