190959-02-5Relevant articles and documents
C26 dialkyl and spiroalkyl analogs of marcfortine A
Lee, Byung H.,Clothier, Michael F.
, p. 1261 - 1266 (1997)
The C26 dimethyl dioxepinoindole ring found in marcfortine A is unique among natural products. In order to ascertain the importance of the dimethyl moiety to anthelmintic activity, we prepared a variety of C26-dialkyl and spiroalkyl analogs. They include cyclobutyl, cyclohexyl, diethyl, and ethyl-methyl derivatives. This communication describes the synthesis of these compounds.
