19128-48-4 Usage
General Description
2-BROMO-1-CHLORO-3-NITROBENZENE is a chemical compound with the molecular formula C6H4BrClNO2. It is a nitrobenzene derivative with a bromo and chloro substituent on the first and second carbon atoms, respectively. 2-BROMO-1-CHLORO-3-NITROBENZENE is commonly used in organic synthesis for the production of various pharmaceuticals, agrochemicals, and dyes. It is also used in some research and development processes, particularly in the field of medicinal chemistry. 2-BROMO-1-CHLORO-3-NITROBENZENE is known to have certain hazards and should be handled and used with proper safety precautions in a controlled environment.
Check Digit Verification of cas no
The CAS Registry Mumber 19128-48-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,1,2 and 8 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 19128-48:
(7*1)+(6*9)+(5*1)+(4*2)+(3*8)+(2*4)+(1*8)=114
114 % 10 = 4
So 19128-48-4 is a valid CAS Registry Number.
InChI:InChI=1S/C6H3BrClNO2/c7-6-4(8)2-1-3-5(6)9(10)11/h1-3H
19128-48-4Relevant articles and documents
Approaches to the synthesis of 2,3-dihaloanilines. Useful precursors of 4-functionalized-1 H-indoles
Guilarte, Veronica,Castroviejo, M. Pilar,Garcia-Garcia, Patricia,Fernandez-Rodriguez, Manuel A.,Sanz, Roberto
experimental part, p. 3416 - 3437 (2011/06/28)
2,3-Dihaloanilines have been proved as useful starting materials for synthesizing 4-halo-1H-indoles. Subsequent or in situ functionalization of the prepared haloindoles allows the access to a wide variety of 2,4- or 2,3,4-regioselectively functionalized indoles in good overall yields. As no efficient synthetic routes to 2,3-dihaloanilines have been described in the literature, different approaches to the preparation of these 1,2,3-functionalized aromatic precursors are now presented. The most general one involves a Smiles rearrangement from the corresponding 2,3-dihalophenols and allows the preparation of 2,3-dihaloanilides in a straightforward and synthetically useful manner.
