1921-70-6 Usage
Description
PRISTANE is a natural saturated terpenoid alkane, an acyclic saturated hydrocarbon derived from phytane by loss of its C-16 terminal methyl group. It is a colorless liquid with various applications in different industries.
Used in Lubricant Industry:
PRISTANE is used as a lubricant due to its hydrocarbon oil properties, providing smooth operation and reducing friction between moving parts.
Used in Transformer Oil Industry:
PRISTANE is used as transformer oil, which is essential for the cooling and insulation of transformers in electrical systems.
Used in Anti-corrosion Applications:
PRISTANE serves as an anti-corrosion agent, protecting metal surfaces from rust and other forms of corrosion, thus extending the life of equipment and structures.
Used in Biological Research:
PRISTANE is used as a biological marker in various research studies, helping scientists track and monitor biological processes and conditions.
Used in Experimental Systems:
PRISTANE is used to induce plasmacytomas in experimental systems, which aids in the study of cancer cell development and behavior.
Used in Monoclonal Antibody Production:
PRISTANE is utilized in the production of monoclonal antibodies, which are essential for research, diagnostics, and therapeutic applications.
Used in Autoimmune Disease Research:
PRISTANE is a hydrocarbon oil adjuvant used in research on the pathogenesis of autoimmune diseases such as arthritis and lupus, providing insights into disease mechanisms and potential treatments.
Used in Inflammation and Myeloma Research:
PRISTANE has been used as an inflammation-inducing agent, leading to myeloma development in BALB/c strain mice, and as a rheumatoid arthritis-inducing agent in rats, contributing to the understanding of these diseases and the development of new therapies.
Biochem/physiol Actions
Pristane is a hydrocarbon oil adjuvant widely used to induce tumorigenesis in mice and arthritis and lupus nephritis in rats. It works as a adjuvant for monoclonal antibody generation in mouse ascites.
Purification Methods
Purify pristane by shaking it with conc H2SO4 (care, if amount of pristane is too small then it should be diluted with pet ether not Et2O which is quite soluble H2SO4), then H2O (care, as it may heat up in contact with conc H2SO4), dry (MgSO4), evaporate and distil it over Na. [S.rensen & S.rensen Acta Chem Scand 3 939 1949, Beilstein 1 III 570.]
Check Digit Verification of cas no
The CAS Registry Mumber 1921-70-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,2 and 1 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1921-70:
(6*1)+(5*9)+(4*2)+(3*1)+(2*7)+(1*0)=76
76 % 10 = 6
So 1921-70-6 is a valid CAS Registry Number.
InChI:InChI=1/C19H40/c1-16(2)10-7-12-18(5)14-9-15-19(6)13-8-11-17(3)4/h16-19H,7-15H2,1-6H3
1921-70-6Relevant articles and documents
Jain,Striha
, p. 4359 (1969)
Greener synthesis of pristane by flow dehydrative hydrogenation of allylic alcohol using a packed-bed reactor charged by pd/c as a single catalyst
Fukuyama, Takahide,Furuta, Akihiro,Hirobe, Yuki,Hyodo, Mamoru,Kasakado, Takayoshi,Ryu, Ilhyong
, (2021/10/05)
Our previous work established a continuous-flow synthesis of pristane, which is a saturated branched alkane obtained from a Basking Shark. The dehydration of an allylic alcohol that is the key to a tetraene was carried out using a packed-bed reactor charged by an acid–silica catalyst (HO-SAS) and flow hydrogenation using molecular hydrogen via a Pd/C catalyst followed. The present work relies on the additional propensity of Pd/C to serve as an acid catalyst, which allows us to perform a flow synthesis of pristane from the aforementioned key allylic alcohol in the presence of molecular hydrogen using Pd/C as a single catalyst, which is applied to both dehydration and hydrogenation. The present one-column-two-reaction-flow system could eliminate the use of an acid catalyst such as HO-SAS and lead to a significant simplification of the production process.
A method for synthesizing basking shark alkane
-
, (2017/08/23)
The present invention discloses a novel method for chemically synthesizing pristane with isophytol as a starting material. Isophytol is used, and pristane is prepared through oxidation, a methyl Grignard reaction, sulfonylation, halogenation and reduction. The method in the present invention, as compared with the conventional synthesizing method, adopts cheap raw materials, avoids high pressure hydrogenation reactions, and solves the problems of methyl migration caused by a dehydration reaction or isomerization caused by cyclization in the conventional synthesizing method. The method of the present invention is suitable for industrial production of pristane.
