19357-01-8Relevant articles and documents
Solvent-mediated one-pot synthesis of cyclic N-Substituted imides
Patil, Sambhaji V.,Mahale, Keshao A.,Gosavi, Kirankumar S.,Deshmukh, Ganesh B.,Patil, Nilesh S.
, p. 314 - 320 (2013/07/26)
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Organic acids as catalysts for the erosion of polymers
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, (2008/06/13)
The invention relates to the use of carboxylic acids incorporated as a catalyst in poly(orthoester)s and other acid labile polymers such that upon exposure to aqueous environments the acid catalyzes the erosion of the polymer matrix. The rate of release of a drug substance incorporated into or surrounded by the poly(orthoester) or other acid labile polymer can be controlled in that the drug is released as the polymer is eroded in response to the catalytic action of the acid incorporated therein.
11a-Methano-TXA compounds
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, (2008/06/13)
The present invention provides novel 11a-methano-TXA compounds and intermediates and processs for their preparation. Further provided are methods for using these novel TXA analogs as inhibitors of thromboxane synthetase, rendering these analogs useful for a variety of pharmacological purposes. These pharmacological uses include anti-inflammatory, anti-thromobitc, and anti-asthma indications.