193630-25-0

Basic information

• Product Name: 1(3H)-Isobenzofuranone, 3-(3-ethyl-4-hydroxyphenyl)-3-(4-hydroxyphenyl)-
• CAS NO: 193630-25-0
• Molecular Formula: C22H18O4
• Molecular Weight: 346.383
• Mol File: 193630-25-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1(3H)-Isobenzofuranone, 3-(3-ethyl-4-hydroxyphenyl)-3-(4-hydroxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1(3H)-Isobenzofuranone, 3-(3-ethyl-4-hydroxyphenyl)-3-(4-hydroxyphenyl)-(193630-25-0)
• EPA Substance Registry System: 1(3H)-Isobenzofuranone, 3-(3-ethyl-4-hydroxyphenyl)-3-(4-hydroxyphenyl)-(193630-25-0)

Safety Data

• Hazardous Substances Data: 193630-25-0(Hazardous Substances Data)

Upstream product

• 90-00-6 o-Hydroxyethylbenzene 
• 85-57-4 2-(4-hydroxy-benzoyl)-benzoic acid 
• 193630-26-1 3-(4''-hydroxyphenyl)-3-(4'-hydroxy-3'-isopropylphenyl)phthalide 
• 854-76-2 [3-(3'-methyl-4'-hydroxyphenyl)-3-(4''-hydroxyphenyl)phthalide] 

Downstream Products

• 83938-70-9 2-(4-hydroxy-3-isopropylbenzoyl)benzoic acid 
• 193630-26-1 3-(4''-hydroxyphenyl)-3-(4'-hydroxy-3'-isopropylphenyl)phthalide 
• 85-57-4 2-(4-hydroxy-benzoyl)-benzoic acid 
• 67217-89-4 2-(3-Ethyl-4-hydroxy-benzoyl)-benzoic acid 

Relevant articles and documents

3,3-Diarylphthalides. Part I. Friedlaender reaction of 3′-alkylphenolphthaleins

Friedlaender reaction was investigated, starting from 3′-alkyl-derivatives of phenolphthalein 1-3 (alkyl = Me, Et and i-Pr) and hydroxylamine in strongly alkaline medium. The process was found to give, after acidic hydrolysis of primarily formed anil-type semi-products, a mixture of two 2-aroylbenzoic acids (2-ABAs) in each case. Identification and quantification of 2-ABAs were carried out within RP-HPLC on ODS column. Based on quantitative results, migratory aptitude (MA) parameter values of ionized 4-hydroxy-3-alkylphenyl nuclei were calculated, taking an unsubstituted ionized 4-hydroxyphenyl ring as a standard.