19506-88-8

Basic information

• Product Name: 2H-Isoindole-2-acetic acid, 1,3-dihydro-1,3-dioxo-a-propyl-
• CAS NO: 19506-88-8
• Molecular Formula: C13H13NO4
• Molecular Weight: 247.251
• Mol File: 19506-88-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2H-Isoindole-2-acetic acid, 1,3-dihydro-1,3-dioxo-a-propyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Isoindole-2-acetic acid, 1,3-dihydro-1,3-dioxo-a-propyl-(19506-88-8)
• EPA Substance Registry System: 2H-Isoindole-2-acetic acid, 1,3-dihydro-1,3-dioxo-a-propyl-(19506-88-8)

Safety Data

• Hazardous Substances Data: 19506-88-8(Hazardous Substances Data)

Upstream product

• 85-44-9 phthalic anhydride 
• 760-78-1 2-aminopentanoic acid 

Downstream Products

• 124-38-9 carbon dioxide 
• 488863-83-8 5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-oxo-2-(triphenyl-λ⁵-phosphanylidene)-octanenitrile 
• 488863-82-7 3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-hexanoic acid 

Relevant articles and documents

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Palladium-Catalyzed Site-Selective Fluorination of Unactivated C(sp3)-H Bonds

The transition-metal-catalyzed direct C-H bond fluorination is an attractive synthetic tool toward the preparation of organofluorines. While many methods exist for the direct sp3 C-H functionalization, site-selective fluorination of unactivated sp3 carbons remains a challenge. Direct, highly site-selective and diastereoselective fluorination of aliphatic amides via a palladium-catalyzed bidentate ligand-directed C-H bond functionalization process on unactivated sp3 carbons is reported. With this approach, a wide variety of β-fluorinated amino acid derivatives and aliphatic amides, important motifs in medicinal and agricultural chemistry, were prepared with palladium acetate as the catalyst and Selectfluor as the fluorine source.