1978-20-7 Usage
Description
3,4-BIS(TRIFLUOROMETHYL)NITROBENZENE is an organic compound characterized by its molecular structure that features two trifluoromethyl groups and a nitro group attached to a benzene ring. 3,4-BIS(TRIFLUOROMETHYL)NITROBENZENE is known for its reactivity and is commonly utilized as a starting material in the synthesis of various organic compounds.
Uses
Used in Pharmaceutical Industry:
3,4-BIS(TRIFLUOROMETHYL)NITROBENZENE is used as a reactant for the synthetic preparation of 4,5-bis(trifluoromethyl)benzimidazole, which is an important intermediate in the development of pharmaceutical compounds. The benzimidazole core is a common structural motif found in many bioactive molecules, making this compound a valuable building block in the synthesis of potential therapeutic agents.
Used in Chemical Synthesis:
In the field of organic chemistry, 3,4-BIS(TRIFLUOROMETHYL)NITROBENZENE serves as a versatile intermediate for the synthesis of a wide range of organic compounds, including those with potential applications in various industries such as agriculture, materials science, and pharmaceuticals. Its unique structure allows for further functionalization and modification, making it a valuable asset in the development of new molecules with desired properties.
Check Digit Verification of cas no
The CAS Registry Mumber 1978-20-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,7 and 8 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1978-20:
(6*1)+(5*9)+(4*7)+(3*8)+(2*2)+(1*0)=107
107 % 10 = 7
So 1978-20-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H3F6NO2/c9-7(10,11)5-2-1-4(15(16)17)3-6(5)8(12,13)14/h1-3H
1978-20-7Relevant articles and documents
Discovery of Potent Antiallergic Agents Based on ano-Aminopyridinyl Alkynyl Scaffold
Bai, Fang,Chen, Taiwen,Fan, Chen,Hu, Youhong,Li, Xin,Liu, Moting,Ma, Yanjie,Tang, Wei,Xiang, Caigui,Xie, Zhicheng
supporting information, p. 13588 - 13603 (2021/09/20)
Effective therapeutic agents are highly desired for immune-mediated allergic diseases. Herein, we report the design, synthesis, and structure-activity relationship of ano-aminopyridinyl alkyne series as novel orally bioavailable antiallergic agents, which