20174-68-9

Basic information

• Product Name: 4-Methyl-2-benzothiazolehydrazine
• Synonyms: 4-METHYL-2-HYDRAZINO BENZOTHIAZOLE;4-methylbenzothiazol-2(3H)-one hydrazone;2-hydrazin-4-methylbenzothiazole;4-METHYL-2(3H)-BENZOTHIAZOLONE YDRAZONE;2(3H)-Benzothiazolone,4-methyl-,hydrazone(9CI);4-METHYL-2(3H)-BENZOTHIAZOLONEHYDRAZONE;4-Methyl-2-benzothiazolehydrazine;4-METHYL-2(3H)-BENZOTHIAZOLONHYDRAZONE
• CAS NO: 20174-68-9
• Molecular Formula: C₈H₉N₃S
• Molecular Weight: 179.24216
• EINECS: 243-562-4
• Product Categories: BENZOTHIAZOLE;Thiazoles;white or white-like crystal
• Mol File: 20174-68-9.mol
• Article Data: 16

Chemical Properties

• Melting Point: 167-169 °C
• Boiling Point: 340.3 °C at 760 mmHg
• Flash Point: 159.6 °C
• Appearance: /
• Density: 1.387g/cm³
• Vapor Pressure: 8.68E-05mmHg at 25°C
• Refractive Index: 1.774
• Storage Temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
• PKA: 2.62±0.20(Predicted)
• CAS DataBase Reference: 4-Methyl-2-benzothiazolehydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methyl-2-benzothiazolehydrazine(20174-68-9)
• EPA Substance Registry System: 4-Methyl-2-benzothiazolehydrazine(20174-68-9)

Safety Data

• Hazardous Substances Data: 20174-68-9(Hazardous Substances Data)

Usage

Uses

2-Hydrazino-4-methylbenzothiazole is used in the synthesis of pesticides.

InChI:InChI=1/C8H9N3S/c1-5-3-2-4-6-7(5)10-8(11-9)12-6/h2-4H,9H2,1H3,(H,10,11)

Upstream product

• 3622-32-0 2-chloro-4-methyl-benzothiazole 
• 3622-20-6 4-methyl-2-methylsulfanyl-1,3-benzothiazole 
• 2268-77-1 2-Mercapto-4-methyl-benzothiazole 
• 53848-17-2 2-bromo-6-methylaniline 
• 64036-72-2 4-methyl-2-aminobenzothiazole hydrochloride 
• 95-53-4 o-toluidine 
• 53065-25-1 4-Methyl-2-dimethylaminobenzothiazole hydrobromide 
• 1477-42-5 4-methyl-1,3-benzothiazol-2-amine 
• 2644-70-4 hydrazine hydrochloride 
• 614-78-8 o-tolylthiourea 
• 53065-21-7 2-amino-4-methylbenzothiazole hydrobromide 

Downstream Products

• 1268376-12-0 3-(3-pyridyl)-5-(4-methoxyphenyl)-4-(N-4-methyl-1,3-benzothiazol-2-amino)-4H-1,2,4-triazole 
• 1316270-44-6 C₂₁H₁₅N₇O₂S 
• 1246493-45-7 3-(3-pyridyl)-5-(4-methylphenyl)-4-(N-(4-methyl-1,3-benzothiazol-2-yl)amino)-4H-1,2,4-triazole 
• 41814-78-2 5-methyl-1,2,4-triazolo[3,4-b]benzothizole 
• 219904-19-5 3-(3-bromo-2-phenyl-propenyl)-5-methyl-benzo[4,5]thiazolo[2,3-c][1,2,4]triazole 
• 219904-17-3 2-acetylhydrazino-4-methylbenzothiazole 
• 3622-32-0 2-chloro-4-methyl-benzothiazole 

Relevant articles and documents

The syntheses and crystal structure of novel 5-methyl-3-substituted-1,2,4-triazolo[3,4-b]benzothiazoles

Novel 5-methyl-3-substituted-1,2,4-triazolo[3,4-b]benzothiazoles were synthesized from o-methylaniline to 5 with various aromatic carbonic acids. The yielded product 6a-e were confirmed by Elemental Analyses, NMR, MS, IR spectra and 6e was investigated with X-ray crystallography. Compound 6e, C24H16N4S, Mr = 392.69, crystallized in the triclinic space group P1? with unit cell parameters a = 9.713(3) ?, b = 14.645(4) ?, c = 15.641(3) ?, α = 113.17(2)°, β=90.11(2)°, γ = 109.29(2)°, V = 1908.1(7) ?3, Z = 4, Dm = 1.366 Mgm-3.

Method for synthesizing 4-methyl-2-benzothiazolehydrazine

The invention discloses a method for synthesizing 4-methyl-2-benzothiazolehydrazine. The method comprises the following steps: carrying out synthesis reaction on o-toluidine and thiocyanate in acid toobtain o-tolylthiourea; carrying out a synthesis reaction on the o-tolylthiourea and a catalyst in water to obtain 2-amino-4-methylbenzothiazole; and carrying out a synthesis reaction on the 2-amino-4-methylbenzothiazole in hydrazine hydrate, so as to obtain the 4-methyl-2-benzothiazolehydrazine. The method for synthesizing the 4-methyl-2-benzothiazolehydrazine, provided by the invention, is simple to operate, less in three wastes, capable of repeatedly applying wastewater, high in product content, good in quality and suitable for industrial mass production.

Production process for 4-methyl-2-hydrazinobenzothiazole

4-methyl-2-hydrazinobenzothiazole is an important intermediate for synthesis of tricyclazole, and the tricyclazole is a main drug for preventing and controlling rice blast and a high-efficiency systemic fungicide, and has high biological activity, a unique action mechanism and special effects on preventing and controlling the rice blast. A current synthetic technology has low reaction efficiency and not high product purity, and produces more three industrial waste (waste water, waste gas and solid waste). The invention overcomes the above disadvantages to provide a production process for the 4-methyl-2-hydrazinobenzothiazole; and the process is realized through the following steps: 1, weighing raw materials for standby application; 2, performing an addition reaction to synthesize o-methylphenyl-thiourea; 3, performing a ring-closure reaction to synthesize 4-methyl-2-aminobenzothiazole hydrochloride; 4, performing a substitution reaction to synthesize the 4-methyl-2-hydrazinobenzothiazole; and 5, performing drying and performing packaging.