2044-64-6 Usage
Description
N,N-Dimethylacetoacetamide (DMAA) is a clear, colorless to yellow liquid that serves as a versatile organic intermediate and co-promoter in various applications. It is soluble in water and is used in the production of low VOC unsaturated polyester (FRP) systems for coatings, as well as an intermediate for the synthesis of insecticides and thioamide compounds.
Uses
Used in Composite and Plastic Industry:
N,N-Dimethylacetoacetamide is used as a general purpose, low color generating co-promoter for many unsaturated polyester (FRP) resin formulations. It enhances the curing process and improves the final properties of the composite materials.
Used in Coatings Industry:
N,N-Dimethylacetoacetamide is used in the production of low VOC unsaturated polyester (FRP) systems for coatings, contributing to the development of environmentally friendly and high-performance coatings.
Used in Pharmaceutical Synthesis:
N,N-Dimethylacetoacetamide is used as an intermediate for the production of thioamide compounds, which have a wide range of applications in pharmaceutical synthesis, chemical engineering, and related fields.
Used in Chemical Engineering:
N,N-Dimethylacetoacetamide is used as a reactant in the asymmetric hydrogenation of functionalized ketones in the presence of chiral bis(diphenylphosphino)binaphthyl ruthenium complex, which is an important process in chemical engineering.
Used in Agrochemical Industry:
N,N-Dimethylacetoacetamide is used as an intermediate for the production of insecticides, such as dicrotophos, helping to develop effective and environmentally friendly pest control solutions.
Used in Catalyst and Stabilizer Production:
Thioamide compounds, which can be prepared using N,N-Dimethylacetoacetamide, are used in the production of polymerization inhibitors, catalysts, stabilizers, and other chemicals, contributing to the advancement of various industrial processes.
Flammability and Explosibility
Nonflammable
Check Digit Verification of cas no
The CAS Registry Mumber 2044-64-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,0,4 and 4 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2044-64:
(6*2)+(5*0)+(4*4)+(3*4)+(2*6)+(1*4)=56
56 % 10 = 6
So 2044-64-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H11NO2/c1-4(8)6(2,3)5(7)9/h1-3H3,(H2,7,9)
2044-64-6Relevant articles and documents
General [4 + 1] Cyclization Approach to Access 2,2-Disubstituted Tetrahydrofurans Enabled by Electrophilic Bifunctional Peroxides
Gao, Min,Zhao, Yukun,Zhong, Chen,Liu, Shengshu,Liu, Pengkang,Yin, Qi,Hu, Lin
supporting information, p. 5679 - 5684 (2019/08/01)
A general [4 + 1] cyclization reaction of carbonyl nucleophiles with 2-iodomethylallyl peroxides, which function as unique electrophilic oxygen synthons, for the synthesis of a broad range of 2,2-disubstituted tetrahydrofurans is achieved under operationally simple conditions. The unprecedented asymmetric version of such reaction is also realized via chiral auxiliary-assisted cyclization, thus providing a distinct approach to access chiral tetrahydrofurans with high diastereoselectivities. The new method can be applied to the synthesis of core structure of posaconazole drug.
Intermolecular acetoxyaminoalkylation of α-diazo amides with (diacetoxyiodo)benzene and amines
D?ben, Nadine,Yan, Hong,Kischkewitz, Marvin,Mao, Jincheng,Studer, Armido
supporting information, p. 7933 - 7936 (2019/01/04)
Multicomponent reactions of diazo compounds have attracted much attention in recent years. Such transformations are generally conducted by applying transition metal catalysis and involve the corresponding metal carbenes as key intermediates. In this letter, a metal-free three-component intermolecular acetoxyaminoalkylation of α-diazo amides with tertiary aryl amines and (diacetoxyiodo)benzene is presented.
Direct synthesis of polysubstituted 2-aminothiophenes by Cu(ii)-catalyzed addition/oxidative cyclization of alkynoates with thioamides
Ge, Li-Shi,Wang, Zheng-Lin,An, Xing-Lan,Luo, Xiaoyan,Deng, Wei-Ping
supporting information, p. 8473 - 8479 (2014/12/10)
A facile and direct synthetic method was developed for the construction of structurally important 2-aminothiophenes in moderate to excellent yields (up to 91%), via Cu(ii)-catalyzed addition/oxidative cyclization of readily available thioamides with alkynoates under an air atmosphere. This journal is