204451-48-9

Basic information

• Product Name: L-GLUTAMINE-15N2
• Synonyms: L-GLUTAMINE-15N2;L-GLUTAMINE-AMINE-15N;L-GLUTAMINE-15N2, 99 ATOM % 15N;l-glutamine-15n298+atom%15n;L-GlutaMine-15N2
• CAS NO: 204451-48-9
• Molecular Formula: C5H10N2O3
• Molecular Weight: 148.16
• Product Categories: Amino Acids 13C, 2H, 15N;Alphabetical Listings;Amino Acids;Amino Acids and DerivativesStable Isotopes;Amino AcidsStable Isotopes;Biomolecular MS;Biomolecular NMR;G-HMass Spectrometry;Labeled Amino AcidsStable Isotopes;Products for SILAC;Proteomics Stable Isotope Labeling;Stable Isotopes
• Mol File: 204451-48-9.mol
• Article Data: 0

Chemical Properties

• Melting Point: 185 °C (dec.)(lit.)
• Appearance: /
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: Aqueous Acid (Slightly), Water (Slightly, Sonicated)
• Stability: Hygroscopic
• CAS DataBase Reference: L-GLUTAMINE-15N2(CAS DataBase Reference)
• NIST Chemistry Reference: L-GLUTAMINE-15N2(204451-48-9)
• EPA Substance Registry System: L-GLUTAMINE-15N2(204451-48-9)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 204451-48-9(Hazardous Substances Data)

Usage

Description

L-GLUTAMINE-15N2, also known as L-Glutamine (15N2, 98%), is a stable isotope-labeled amino acid with nitrogen-15 (15N) incorporated into its structure. It is a solid compound and serves as a valuable intermediate in various biochemical and pharmaceutical applications due to its unique isotopic properties.

Uses

Used in Enzymatic Synthesis:
L-GLUTAMINE-15N2 is used as an intermediate in the enzymic synthesis of glycine from glyoxylic acid and glutamine. The incorporation of nitrogen-15 (15N) in the α-amino group allows for the tracking and analysis of metabolic pathways and enzymatic reactions, providing insights into the biochemical processes.
Used in Pharmaceutical Research:
L-GLUTAMINE-15N2 is utilized in pharmaceutical research as a stable isotope-labeled compound to study drug metabolism, pharmacokinetics, and pharmacodynamics. The presence of 15N enables researchers to differentiate between the labeled compound and its metabolites, facilitating the understanding of drug action and safety profiles.
Used in Biochemical Studies:
In biochemical studies, L-GLUTAMINE-15N2 serves as a valuable tool for investigating enzyme mechanisms, substrate specificity, and reaction kinetics. The isotopic labeling allows for the detection and quantification of reaction intermediates and products, contributing to a deeper understanding of enzymatic processes.
Used in Nutritional Research:
L-GLUTAMINE-15N2 is employed in nutritional research to study the metabolism and utilization of amino acids in the body. The stable isotope labeling provides a means to trace the incorporation of L-glutamine into proteins and other biomolecules, offering insights into the role of this amino acid in health and disease.
Used in Diagnostic Applications:
L-GLUTAMINE-15N2 can be used in diagnostic applications to develop and improve tests for various metabolic disorders and diseases. The isotopic labeling allows for the sensitive detection and quantification of specific compounds and metabolites, aiding in the diagnosis and monitoring of conditions related to amino acid metabolism.