2045-19-4Relevant articles and documents
The bivalent ligand approach as a tool for improving the in vitro anti-alzheimer multitarget profile of dimebon
Rosini, Michela,Simoni, Elena,Bartolini, Manuela,Soriano, Elena,Marco-Contelles, Jose,Andrisano, Vincenza,Monti, Barbara,Windisch, Manfred,Hutter-Paier, Birgit,Mcclymont, David W.,Mellor, Ian R.,Bolognesi, Maria Laura
, p. 1276 - 1281 (2013)
Inspired by the concept of bivalent ligands, we prepared a small set of analogues of the drug candidate dimebon. They were shown to inhibit AChE, Aβ42 aggregation, and NMDA receptor activation to a greater extent than dimebon. Some of these compounds also enhanced the survival of chicken neurons under apoptosis-inducing conditions. Copyright
Chiral fluorescence sensor as well as preparation method and application thereof in chiral amino acid recognition
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Paragraph 0030; 0032; 0039-0041, (2021/05/29)
The invention discloses a binaphthol derivative shown as a formula I or a stereoisomer thereof. The binaphthol derivative is obtained by carrying out condensation reaction on a binaphthol derivative with chirality and N,N-bis(2-bromoethyl)aniline and then
A near IR di-styryl BODIPY-based ratiometric fluorescent chemosensor for Hg(II)
Atilgan, Serdar,Kutuk, Ilker,Ozdemir, Tugba
supporting information; experimental part, p. 892 - 894 (2010/05/03)
A novel BODIPY-based near-IR emitting probe as a selective and sensitive fluorophore for Hg(II) is synthesized. This versatile BODIPY fluorophore is functionalized for long wavelength emission at the 3 and 5 positions via a condensation reaction in which