205318-86-1

Basic information

• Product Name: 2-{3-[4-(3-hydroxy-propyl)-phenoxy]-propyl}-isoindole-1,3-dione
• Synonyms: 2-{3-[4-(3-hydroxy-propyl)-phenoxy]-propyl}-isoindole-1,3-dione
• CAS NO: 205318-86-1
• Molecular Weight: 339.391
• Mol File: 205318-86-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-{3-[4-(3-hydroxy-propyl)-phenoxy]-propyl}-isoindole-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{3-[4-(3-hydroxy-propyl)-phenoxy]-propyl}-isoindole-1,3-dione(205318-86-1)
• EPA Substance Registry System: 2-{3-[4-(3-hydroxy-propyl)-phenoxy]-propyl}-isoindole-1,3-dione(205318-86-1)

Safety Data

• Hazardous Substances Data: 205318-86-1(Hazardous Substances Data)

Upstream product

• 501-97-3 4-hydroxyphenylpropionic acid 
• 23795-02-0 3-(4-hydroxy-phenyl)-propionic acid ethyl ester 
• 5460-29-7 2-(3-bromopropyl)isoindole-1,3-dione 
• 10210-17-0 3-(4-hydroxyphenyl)propan-1-ol 

Downstream Products

• 910303-11-6 3-[4-(amino-propoxy)-phenyl]-propan-1-ol 
• 205318-89-4 2-[3-(4-{3-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-yl]-propyl}-phenoxy)-propyl]-isoindole-1,3-dione 
• 205318-90-7 3-(4-{3-[4-(2-benzhydryloxy-ethyl)-piperazine-1-yl]-propyl}-phenoxy)-propylamine 
• 205318-88-3 2-{3-[4-(3-Piperazin-1-yl-propyl)-phenoxy]-propyl}-isoindole-1,3-dione 
• 910303-13-8 3-{4-[3-(acridin-9-ylamino)-propoxy]-phenyl}-propan-1-ol 
• 205318-87-2 methanesulfonic acid 3-{4-[3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propoxy]phenyl}-propylester 

Relevant articles and documents

Synthesis and radioiodination of some 9-aminoacridine derivatives for potential use in radionuclide therapy

Three derivatives of the DNA intercalating compound 9-aminoacridine, were prepared and radioiodinated for biological experiments. The compounds are the stannyl derivatives 3-{4-[3-(acridin-9-ylamino)-propoxy]-3-trimethylstannyl- phenyl}-propionic acid and acridin-9-yl-{3-[4-(2-amino-ethyl)-2- trimethylstannyl-phenoxy]-propyl}-amine which were synthesized from the corresponding iodo derivatives by palladium catalyzed reactions, and 4-[2-(acridin-9-ylamino)-ethyl]-phenol. The two stannylated compounds and the phenol were used as precursors for radioiodination and were labeled with 125I using chloramine-T as an oxidant achieving high-to-excellent yields. Copyright