20601-22-3

Basic information

• Product Name: 2-Bromo-1-methylnaphthalene
• Synonyms: 2-Bromo-1-methylnaphthalene
• CAS NO: 20601-22-3
• Molecular Formula: C₁₁H₉Br
• Molecular Weight: 221.1
• Mol File: 20601-22-3.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 300.9°C at 760 mmHg
• Flash Point: 137.4°C
• Appearance: /
• Density: 1.417g/cm³
• Vapor Pressure: 0.00195mmHg at 25°C
• Refractive Index: 1.645
• CAS DataBase Reference: 2-Bromo-1-methylnaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-1-methylnaphthalene(20601-22-3)
• EPA Substance Registry System: 2-Bromo-1-methylnaphthalene(20601-22-3)

Safety Data

• Hazardous Substances Data: 20601-22-3(Hazardous Substances Data)

Usage

General Description

2-Bromo-1-methylnaphthalene is a chemical compound with the molecular formula C11H9Br. It is a halogenated derivative of 1-methylnaphthalene, and it consists of a naphthalene ring with a methyl group and a bromine atom attached at specific positions. This chemical is commonly used in organic synthesis and pharmaceutical research as a reagent and intermediate due to its reactive nature and ability to undergo various chemical reactions. It is also employed in the manufacturing of dyes, fragrances, and other aromatic compounds. However, 2-Bromo-1-methylnaphthalene may pose health and environmental risks, and appropriate safety measures must be taken when handling and using this compound.

InChI:InChI=1/C11H9Br/c1-8-10-5-3-2-4-9(10)6-7-11(8)12/h2-7H,1H3

Upstream product

• 75-25-2 Bromoform 
• 767-60-2 3-Methylindene 
• 865-47-4 potassium tert-butylate 
• 66768-77-2 4-Brom-5-methyl-1-benzothiepin 
• 880-93-3 4-nitro-1-methylnaphthalene 
• 91-57-6 2-Methylnaphthalene 
• 90-12-0 1-Methylnaphthalene 
• 83-33-0 inden-1-one 
• 53870-83-0 1-methyl-2-bromo-4-nitronaphthalene 
• 64666-42-8 1-methyl-1-indanol 
• 63017-87-8 2-nitro-1-methylnaphthalene 
• 767-59-9 1-Methylinden 
• 23683-32-1 1-methyl-2-bromo-4-aminonaphthalene 
• 771-13-1 1-methylnaphthalen-2-amine 

Downstream Products

• 590401-47-1 (1-methylnaphthalen-2-yl)boronic acid 
• 93322-80-6 1-methyl-2-thiophenylnaphthalene 

Relevant articles and documents

Towards the isomer-specific synthesis of higher fullerenes and buckybowls by the surface-catalyzed cyclodehydrogenation of aromatic precursors

Fullerenes on a plate: A surface-catalyzed cyclodehydrogenation reaction enabled selective fullerene-cage formation from polycyclic organic precursors. As no C-C bond rearrangement occurred during the reaction, only specifically designed precursors gave the desired fullerene (see picture). This efficient and selective condensation process opens new horizons in the directed synthesis of fullerenes and related structures. Copyright

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Chiral Ligand-Mediated Nucleophilic Aromatic Substitution of Naphthoic Acids: A Fast and Efficient Access to Axially Chiral Biaryls

A transition metal-free synthesis of enantioenriched biaryls from aryllithium species has been developed. This approach relies on atropoenantioselective nucleophilic aromatic substitution (SNAr) reaction of unprotected naphthoic acids. The ability of a diverse set of chiral ligands to mediate this transformation has been investigated. 1,2-diether ligands outperform their diamine counterparts and the best enantiocontrol was obtained with readily accessible enantiopure trans-1,2-dimethoxycyclohexane. This SNAr reaction offers an efficient and rapid access to enantioenriched binaphthalenes, phenylnaphthalene, and phenanthrylnaphthalenes (up to 94:6 er).

A concise synthesis of novel naphtho[a]carbazoles and benzo[c]carbazoles

Starting from simple indole precursors the synthesis of naphtho[a]carbazoles and benzo[c]carbazoles is described. Key steps include the use of the Suzuki-Miyaura reaction to afford 2- or 3-aryl substituted indoles, as well as a potassium t-butoxide and light assisted aromatic ring-forming reaction.