20635-51-2Relevant articles and documents
Synthesis of a novel quinoline derivative, 2-(2-methylquinolin-4-ylamino)-N-phenylacetamide - A potential antileishmanial agent
Sahu, Niranjan P.,Pal, Chiranjib,Mandal, Nirup B.,Banerjee, Sukdeb,Raha, Mausumi,Kundu, Ashis P.,Basu, Anirban,Ghosh, Monidipa,Roy, Keshab,Bandyopadhyay, Santu
, p. 1687 - 1693 (2002)
Some novel quinoline derivatives were prepared and tested for antileishmanial activity. 2-(2-Methylquinolin-4-ylamino)-N-phenylacetamide (2) was found to be significantly more active than the standard antileishmanial drug sodium antimony gluconate (SAG) i
A study of diketopiperazines as electron-donor initiators in transition metal-free haloarene-arene coupling
Cumine, Florimond,Zhou, Shengze,Tuttle, Tell,Murphy, John A.
, p. 3324 - 3336 (2017/04/21)
Several diketopiperazines have been shown to promote carbon-carbon coupling between benzene and aryl halides in the presence of potassium tert-butoxide and without the assistance of a transition metal catalyst. The structure of the diketopiperazine has an influence on its reductive potential and can help to promote the coupling of the more challenging aryl bromides with benzene.
Efficient synthesis of piperazinediones using potassium iodide catalysis in aqueous media
Wen, Yong-Hong,Chen, Xiao-Na,Wen, Hui-Ling,Tang, Xiao-Fang
, p. 732 - 736 (2012/06/01)
A simple and efficient synthetic approach to 1,4-disubstituted piperazine-2,5-diones was developed. A series of symmetrical 1,4-disubstituted piperazine-2,5-diones was prepared from chloroacetamides using potassium iodide catalysis in acetone/water. The structures of two products were confirmed by single crystal X-ray diffraction analysis.
