206860-48-2

Basic information

• Product Name: 4-Fluoro-2-(trifluoromethyl)benzyl bromide
• Synonyms: 4-FLUORO-2-(TRIFLUOROMETHYL)BENZYL BROMIDE;ALPHA-BROMO-2-FLUORO-4-(TRIFLUOROMETHYL)TOLUENE;ALPHA-BROMO-4-FLUORO-2-(TRIFLUOROMETHYL)TOLUENE;2-FLUORO-4-(TRIFLUOROMETHYL)BENZYL BROMIDE;1-(BROMOMETHYL)-4-FLUORO-2-(TRIFLUOROMETHYL)BENZENE;a-Bromo-4-fluoro-2-(trifluoromethyl)toluene;4-Fluoro-2-(trifluoromethyl)benzyl bromide, 97+%;à-bromo-4-fluoro-2-(trifluoromethyl)toluene
• CAS NO: 206860-48-2
• Molecular Formula: C₈H₅BrF₄
• Molecular Weight: 257.02
• EINECS: -0
• Product Categories: Fluoro-contained benzyl bromide series;Aromatic Halides (substituted);Aryl;Building Blocks;C8;Chemical Synthesis;Fluorinated Building Blocks;Halogenated Hydrocarbons;Organic Building Blocks;Organic Fluorinated Building Blocks;Trifluoromethyl
• Mol File: 206860-48-2.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 141 °C(lit.)
• Flash Point: 185 °F
• Appearance: Clear colorless to pale yellow/Liquid
• Density: 1.665 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.772mmHg at 25°C
• Refractive Index: n20/D 1.482(lit.)
• Sensitive: Lachrymatory
• CAS DataBase Reference: 4-Fluoro-2-(trifluoromethyl)benzyl bromide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Fluoro-2-(trifluoromethyl)benzyl bromide(206860-48-2)
• EPA Substance Registry System: 4-Fluoro-2-(trifluoromethyl)benzyl bromide(206860-48-2)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-27-36/37/39-45
• RIDADR: UN 2927 6.1/PG 2
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 206860-48-2(Hazardous Substances Data)

Usage

General Description

4-Fluoro-2-(trifluoromethyl)benzyl bromide is a chemical compound with the molecular formula C8H5BrF4. It is a colorless liquid with a strong, pungent odor. 4-Fluoro-2-(trifluoromethyl)benzyl bromide is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is a versatile building block in organic synthesis, often employed as a bromide source for palladium-catalyzed cross-coupling reactions. Additionally, 4-Fluoro-2-(trifluoromethyl)benzyl bromide is used as a reagent in the preparation of various fluorinated organic compounds, which find application in the field of medicinal chemistry and materials science. Due to its potential toxicity and reactivity, it is important to handle and store this compound with proper care and caution.

InChI:InChI=1/C8H5BrF4/c9-4-5-1-2-6(10)3-7(5)8(11,12)13/h1-3H,4H2

Downstream Products

• 1228439-44-8 C₂₂H₂₁F₄NO₃ 
• 1228439-96-0 C₂₅H₂₇F₄NO₄