206878-19-5

Basic information

• Product Name: 5-Acetyl-1-(3-(1-methyl-1,2,3,6-tetrahydropyrid-5-yl)phenyl)benzimidazole O-ethyl oxime
• CAS NO: 206878-19-5
• Molecular Weight: 374.486
• Mol File: 206878-19-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Acetyl-1-(3-(1-methyl-1,2,3,6-tetrahydropyrid-5-yl)phenyl)benzimidazole O-ethyl oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Acetyl-1-(3-(1-methyl-1,2,3,6-tetrahydropyrid-5-yl)phenyl)benzimidazole O-ethyl oxime(206878-19-5)
• EPA Substance Registry System: 5-Acetyl-1-(3-(1-methyl-1,2,3,6-tetrahydropyrid-5-yl)phenyl)benzimidazole O-ethyl oxime(206878-19-5)

Safety Data

• Hazardous Substances Data: 206878-19-5(Hazardous Substances Data)

Upstream product

• 57976-57-5 3-(pyridin-3-yl)aniline 
• 400-93-1 3-nitro-4-fluoroacetophenone 

Relevant articles and documents

1-phenyl-benzimidazole compounds and their use as GABA-a receptor modulators

The present invention relates to novel benzimidazole compounds, represented by general formula (I) in which o is 0, 1, 2 or 3; R1represents an alkyl group, a phenyl group, or a monocyclic heterocyclic group, which groups may be substituted one or more times with substituents selected from alkyl, cycloalkyl, cycloalkyl-alkyl, alkoxy, halogen, trifluoromethyl, cyano, amino and nitro; or R1represents a cyano group or a group of the formula -alkyl-CO2R2, alkenyl-CO2R2, —CO—R2, —CO2(CH2)mR2, or —C(R3)═N—OR2, R11represents a group of formula —CO2—R9, or R11represents a group of general formula (II) in which n is 0, 1, 2 or 3; or R11may represent a group of general formula (III), in which n is 0, 1, 2 or 3; the novel compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABAAreceptor complex, such as for example anxiety, sleep disorders, anaestesia, memory disorders, and epilepsia or other convulsive disorders.