208177-07-5

Basic information

• Product Name: 1,2-Ethenediamine, 1,2-dichloro-N,N'-bis(4-fluorophenyl)-N,N'-dimethyl-
• CAS NO: 208177-07-5
• Molecular Formula: C16H14Cl2F2N2
• Molecular Weight: 343.203
• Mol File: 208177-07-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,2-Ethenediamine, 1,2-dichloro-N,N'-bis(4-fluorophenyl)-N,N'-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Ethenediamine, 1,2-dichloro-N,N'-bis(4-fluorophenyl)-N,N'-dimethyl-(208177-07-5)
• EPA Substance Registry System: 1,2-Ethenediamine, 1,2-dichloro-N,N'-bis(4-fluorophenyl)-N,N'-dimethyl-(208177-07-5)

Safety Data

• Hazardous Substances Data: 208177-07-5(Hazardous Substances Data)

Upstream product

• 142212-08-6 N-(4-fluorophenyl)-N-methylformamide 

Downstream Products

• 773-91-1 5-fluoro-1-methylisatin 

Relevant articles and documents

Umpoled Vilsmeier reagents. The chemistry of aminochlorocarbenes derived from Vilsmeier reagents by the action of bases

Vilsmeier reagents such as N-methyl-N-phenylchloroiminium chloride are readily deprotonated by tert-amines even in POCl3 solution. The resulting transient intermediates, aminochlorocarbenes, are nucleophilic (i.e. umpoled Vilsmeier reagents) and are trapped with electrophiles. In this way dimers [1,2-bis(N-methylanilino)-1,2-dichloroethanes] 3, 'trimers' (indolo[3,2-b]quinolininium chlorides) 4 and 5, 'tetramers' (2,2′-bis-indoles) 11 and isatins 9 and 10 are accessible in one-pot processes from the formanilide.