210163-00-1

Basic information

• Product Name: 3-(6-chloro-9H-purin-9-yl)-1-N-[(N-tert-butyloxycarbonyl-O-carbobenzyloxy)amino]propane
• Synonyms: 3-(6-chloro-9H-purin-9-yl)-1-N-[(N-tert-butyloxycarbonyl-O-carbobenzyloxy)amino]propane
• CAS NO: 210163-00-1
• Molecular Weight: 461.905
• Mol File: 210163-00-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(6-chloro-9H-purin-9-yl)-1-N-[(N-tert-butyloxycarbonyl-O-carbobenzyloxy)amino]propane(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(6-chloro-9H-purin-9-yl)-1-N-[(N-tert-butyloxycarbonyl-O-carbobenzyloxy)amino]propane(210163-00-1)
• EPA Substance Registry System: 3-(6-chloro-9H-purin-9-yl)-1-N-[(N-tert-butyloxycarbonyl-O-carbobenzyloxy)amino]propane(210163-00-1)

Safety Data

• Hazardous Substances Data: 210163-00-1(Hazardous Substances Data)

Upstream product

• 944-81-0 3-(6-chloro-9H-purin-9-yl)propan-1-ol 
• 87-42-3 6-chloro-1H-purine 

Relevant articles and documents

Syntheses of novel hydroxylamine carbanucleosides

Enantiomerically pure 4'-hydroxylamino-adenine-derived carbanucleosides have been synthesized as isosteric 4'-hydroxymetyl analogs to carbovir, ddA, and aristeromycin. The key steps in the syntheses involved an enzymatic desymmetrization, two subsequent Mitsunobu reactions, and a highly diastereoselective ruthenium tetroxide-mediated dithydroxylation, overcoming the syn-directing effect seen in osmium tetroxide-mediated dihydroxylations. Hydroxylamino-propane analogs were also synthesized through similar methodology to afford adenine and cyclopropylamino purine analogs to acyclovir.