21079-31-2 Usage
Description
(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)acetic acid, commonly known as methotrexate, is a potent pharmaceutical compound with a complex chemical structure. It is primarily recognized for its ability to disrupt the rapid growth and reproduction of certain cells within the body, making it a versatile medication for various medical applications.
Uses
Used in Cancer Treatment:
Methotrexate is utilized as a chemotherapeutic agent for the treatment of various types of cancer. It is particularly effective against rapidly dividing cancer cells, helping to slow or halt tumor progression. Methotrexate is often administered in combination with other cancer treatments to enhance overall therapeutic efficacy.
Used in Autoimmune Disease Management:
In the context of autoimmune diseases, methotrexate serves as a disease-modifying antirheumatic drug (DMARD). It is used to reduce inflammation and manage symptoms associated with conditions such as rheumatoid arthritis, psoriasis, and lupus. Methotrexate's ability to suppress the immune system makes it a valuable tool in controlling these diseases.
Used in Termination of Ectopic Pregnancies:
Methotrexate is also employed in the medical termination of ectopic pregnancies, where the fertilized egg implants outside the uterus. By inhibiting the growth of rapidly dividing cells, it can effectively stop the development of the pregnancy and induce its termination.
Used in Pharmaceutical Formulations:
Methotrexate is commonly formulated as a pill or injection for systemic administration. This allows for targeted delivery to areas where its anti-proliferative and anti-inflammatory effects are most needed, ensuring optimal therapeutic outcomes.
Check Digit Verification of cas no
The CAS Registry Mumber 21079-31-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,0,7 and 9 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 21079-31:
(7*2)+(6*1)+(5*0)+(4*7)+(3*9)+(2*3)+(1*1)=82
82 % 10 = 2
So 21079-31-2 is a valid CAS Registry Number.
21079-31-2Relevant articles and documents
Effect of ph, buffer, and viscosity on the photolysis of formylmethylflavin: A kinetic study
Ahmad, Iqbal,Mirza, Tania,Iqbal, Kefi,Ahmed, Sofia,Sheraz, Muhammad Ali,Vaid, Faiyaz H.M.
, p. 579 - 585 (2013/07/28)
The kinetics of the photolysis of formylmethylflavin, a major intermediate product in the aerobic and anaerobic photolysis of riboflavin, was studied in the pH range 2.0-11.0. Formylmethylflavin and its photoproducts, lumichrome and lumiflavin, were determined in degraded solutions using a specific multicomponent spectrophotometric method. The photolysis of formylmethylflavin in alkaline medium takes place by first-order kinetics and the rate constants (kobs) at pH 7.5-11.0 range from 0.27×10-4 to 3.88×10-4 and 0.36×10-4 to 5.63×10-4s-1 under aerobic and anaerobic conditions respectively. In acid medium, the photolysis involves a second-order mechanism and the rate constants at pH 2.0-7.0 range from 1.37 to 2.11 and 2.03 to 2.94M-1s-1 under aerobic and anaerobic conditions respectively. The rate-pH profiles for the photolysis reactions indicate the highest rate of formylmethylflavin degradation is at ～pH 4 and above pH 10. In the alkaline region, the increase in rate with pH is due to higher reactivity of the flavin triplet state. The photolysis of formylmethylflavin is catalyzed by phosphate ions and is affected by the solvent viscosity.
