2114-03-6

Basic information

• Product Name: 1-Propanone, 2,2-dibromo-1-phenyl-
• CAS NO: 2114-03-6
• Molecular Formula: C9H8Br2O
• Molecular Weight: 291.97
• Mol File: 2114-03-6.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: 1-Propanone, 2,2-dibromo-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanone, 2,2-dibromo-1-phenyl-(2114-03-6)
• EPA Substance Registry System: 1-Propanone, 2,2-dibromo-1-phenyl-(2114-03-6)

Safety Data

• Hazardous Substances Data: 2114-03-6(Hazardous Substances Data)

Usage

Physical state

Pale yellow solid at room temperature, describing the appearance of the compound under normal conditions.

Uses

Mainly used in organic synthesis and as an intermediate in the production of pharmaceuticals and agrochemicals, indicating its applications in creating other compounds and its role in the manufacturing process of certain products.

Hazardous nature

Potentially hazardous, as it may cause skin and eye irritation, highlighting the need for caution when handling the compound.

Handling precautions

Should be handled with caution in a well-ventilated area and with appropriate protective equipment, emphasizing the importance of safety measures while working with this chemical.

Flammability

Flammable, indicating the compound can easily catch fire and burn.

Storage and handling

Should be stored and handled in accordance with standard safety procedures for flammable substances, ensuring that proper measures are taken to prevent fire and other hazards associated with flammable materials.

Upstream product

• 93-55-0 1-phenyl-propan-1-one 
• 108-86-1 bromobenzene 
• 93-54-9 1-Phenyl-1-propanol 
• 673-32-5 1-Phenylprop-1-yne 
• 64-19-7 acetic acid 
• 2114-00-3 2-bromo-1-phenyl-1-propanone 

Downstream Products

• 78844-11-8 ((2S,3R)-2-Methyl-3-octyl-oxiranyl)-phenyl-methanone 
• 20365-32-6 3-(4-chlorophenyl)-2-methyl-1-phenyl-2-propen-1-one 
• 1068459-82-4 3-bromo-3-phenylhex-5-en-2-one 
• 14195-15-4 α-(p-methylbenzenesulfonyl)propiophenone 
• 27839-91-4 1-phenyl-2-(phenylsulfonyl)-propan-1-one 
• 14723-74-1 2-(methylsulfonyl)-1-phenylpropan-1-one 
• 91781-50-9 α-<(p-chlorophenyl)sulfonyl>propiophenone 
• 57711-28-1 1,1-dimethoxy-1-phenylpropan-2-one 

Relevant articles and documents

Electrochemical Oxidative Functionalization of Arylalkynes: Access to α,α-Dibromo Aryl Ketones

A general and effective protocol to synthesize α,α-dibromo aryl ketones has been developed via an electrochemical oxidative method. The reaction proceeds smoothly at room temperature in an undivided cell without the addition of external oxidants. In the reaction process, LiBr acts as both bromine source and supporting electrolyte. This electrooxidation strategy has good substrate applicability and functional group compatibility. Moreover, the reaction could be scaled up efficiently in a continuous flow cell. The target product could undergo further functionalization for the synthesis of some useful heterocyclic compounds. (Figure presented.).

Highly efficient recyclable sol gel polymer catalyzed one pot difunctionalization of alkynes

Amino-bridged gel polymer P1 was discovered to catalyze alkyne halo-functionalization in excellent yields, regioselectivity, functional group compatibility, and recyclability. We have observed that both aromatic and aliphatic alkynes can be converted to α,α-dihalogenated ketones in the presence of polymer P1 under metal-free conditions at room temperature within a short reaction time.

Water-controlled selective preparation of α-mono or α,α′-dihalo ketones: Via catalytic cascade reaction of unactivated alkynes with 1,3-dihalo-5,5-dimethylhydantoin

The control of a reaction that can produce multiple products from the same starting material is a highly attractive and challenging concept in organic synthesis. An efficient protocol for the selective synthesis of α-mono or α,α′-dihalo ketones via a water-controlled three-component thiourea-catalyzed cascade reaction of unactivated alkynes, 1,3-dihalo-5,5-dimethylhydantoin and water has been developed. α-Monohaloketones were obtained in aqueous acetone at 45 °C; conversely, α,α′-dihalo ketones were formed with pure water as the sole solvent at room temperature.