21675-47-8 Usage
Description
D-xylo-2-hexulosonic acid, also known as 2-keto-D-gulonic acid, is an organic compound that serves as a crucial precursor in the biosynthesis of vitamin C. It is a key intermediate in the metabolic pathway leading to the production of this essential vitamin, which plays a vital role as a physiological antioxidant and coenzyme in various hydroxylation reactions. Furthermore, D-xylo-2-hexulosonic acid is necessary for the synthesis of collagen, a critical structural protein in the human body.
Uses
Used in Pharmaceutical Industry:
D-xylo-2-hexulosonic acid is used as a precursor for the production of vitamin C, which is essential for maintaining overall health and well-being. Vitamin C is known for its antioxidant properties and its role as a coenzyme in numerous hydroxylation reactions, making it a vital component in the synthesis of various biological molecules.
Used in Nutritional Supplements:
D-xylo-2-hexulosonic acid is utilized in the development of nutritional supplements that aim to provide individuals with the necessary amount of vitamin C to support their immune system, skin health, and overall physiological functions.
Used in Collagen Synthesis:
As a precursor for vitamin C, D-xylo-2-hexulosonic acid plays a crucial role in the synthesis of collagen, a structural protein that is vital for maintaining the integrity and elasticity of skin, bones, and connective tissues. This makes it an important component in products targeting skin health and joint support.
Used in Cosmetics Industry:
D-xylo-2-hexulosonic acid is employed in the formulation of cosmetic products, particularly those that focus on skin health and rejuvenation. Its role in collagen synthesis contributes to the development of products that aim to improve skin elasticity, reduce the appearance of wrinkles, and promote a youthful complexion.
Check Digit Verification of cas no
The CAS Registry Mumber 21675-47-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,6,7 and 5 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 21675-47:
(7*2)+(6*1)+(5*6)+(4*7)+(3*5)+(2*4)+(1*7)=108
108 % 10 = 8
So 21675-47-8 is a valid CAS Registry Number.
21675-47-8Relevant articles and documents
Expanding the reaction space of aldolases using hydroxypyruvate as a nucleophilic substrate
De Berardinis, Véronique,Guérard-Hélaine, Christine,Darii, Ekaterina,Bastard, Karine,Hélaine, Virgil,Mariage, Aline,Petit, Jean-Louis,Poupard, Nicolas,Sánchez-Moreno, Israel,Stam, Mark,Gefflaut, Thierry,Salanoubat, Marcel,Lemaire, Marielle
, p. 519 - 526 (2017/08/14)
Aldolases are key biocatalysts for stereoselective C-C bond formation allowing access to polyoxygenated chiral units through direct, efficient, and sustainable synthetic processes. The aldol reaction involving unprotected hydroxypyruvate and an aldehyde offers access to valuable polyhydroxy-α-keto acids. However, this undescribed aldolisation is highly challenging, especially regarding stereoselectivity. This reaction was explored using, as biocatalysts, a collection of aldolases selected from biodiversity. Several enzymes that belong to the same pyruvate aldolase Pfam family (PF03328) were found to produce the desired hexulosonic acids from hydroxypyruvate and d-glyceraldehyde with complementary stereoselectivities. One of them was selected for the proof of concept as a biocatalytic tool to prepare five (3S,4S) aldol adducts through an eco-friendly process.
