21905-56-6

Basic information

• Product Name: METHYL 2-PHENOXYBENZOATE
• Synonyms: METHYL 2-PHENOXYBENZOATE;RARECHEM AL BF 1507;2-Phenoxybenzoicacidmethylester;2-Phenoxy-benzoicacidmethylester;Benzoic acid, 2-Phenoxy-, methyl ester
• CAS NO: 21905-56-6
• Molecular Formula: C₁₄H₁₂O₃
• Molecular Weight: 228.24
• EINECS: -0
• Mol File: 21905-56-6.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 130°C 0,5mm
• Flash Point: 130°C/0.5mm
• Appearance: /
• Density: 1.153g/cm³
• Vapor Pressure: 0.000317mmHg at 25°C
• Refractive Index: 1.5760
• Storage Temp.: Sealed in dry,Room Temperature
• BRN: 2115719
• CAS DataBase Reference: METHYL 2-PHENOXYBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2-PHENOXYBENZOATE(21905-56-6)
• EPA Substance Registry System: METHYL 2-PHENOXYBENZOATE(21905-56-6)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 21905-56-6(Hazardous Substances Data)

Usage

Description

METHYL 2-PHENOXYBENZOATE is an organic compound that serves as a valuable synthesis intermediate in the chemical industry. It is characterized by its unique chemical structure, which allows for the creation of various derivatives with potential applications in different fields.

Uses

Used in Pharmaceutical Industry:
METHYL 2-PHENOXYBENZOATE is used as a synthesis intermediate for the preparation of hydrazides and hydrazones of phenoxy acetic. These compounds exhibit analgesic properties, making them valuable in the development of pain-relieving medications.
Used in Chemical Synthesis:
In the chemical industry, METHYL 2-PHENOXYBENZOATE is utilized as a key intermediate in the synthesis of various compounds with potential applications in different sectors, such as pharmaceuticals, agrochemicals, and materials science. Its versatility in chemical reactions enables the creation of a wide range of products with diverse functionalities.

InChI:InChI=1/C14H12O3/c1-16-14(15)12-9-5-6-10-13(12)17-11-7-3-2-4-8-11/h2-10H,1H3

Upstream product

• 18052-27-2 tert-butyldimethyl(phenoxy)silane 
• 610-97-9 o-iodo-methyl-benzoic acid 
• 66003-76-7 Diphenyliodonium triflate 
• 119-36-8 methyl salicylate 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 2243-42-7 2-phenoxybenzoic acid 
• 4688-74-8 phenylboric acid 
• 108-95-2 phenol 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 67-56-1 methanol 

Downstream Products

• 2243-42-7 2-phenoxybenzoic acid 
• 361212-34-2 5-((2-phenoxybenzyloxy)methyl)-3-triphenylmethyl-4,5,6,7-tetrahydro-3H-benzimidazole 
• 82657-72-5 2-bromomethylphenyl phenyl ether 
• 140438-10-4 10-methoxydibenzo[b,f][1,4]oxazepin-11(10H)-one 
• 120041-56-7 N-methoxy-2-phenoxybenzamide 
• 3991-61-5 1-methyl-2-phenoxybenzene 
• 90-47-1 xanth-9-one 
• 108-95-2 phenol 
• 119-36-8 methyl salicylate 
• 6476-32-0 o-phenoxybenzonitrile 
• 618429-99-5 5-(2-phenoxyphenyl)-2H-1,2,4-triazole-3(4H)-thione 
• 13807-84-6 (2-phenoxyphenyl)methanol 
• 618430-11-8 3-ethoxy-5-(2-phenoxy-phenyl)-4H-[1,2,4]triazole 
• 618430-17-4 2-amino-5-(2-phenoxyphenyl)-1,3,4-oxadiazole 

Relevant articles and documents

One-pot synthesis of xanthones and thioxanthones by the tandem coupling-cyclization of arynes and salicylates

(Chemical Equation Presented) The reaction of silylaryl triflates, CsF, and salicylates affords a general and efficient way to prepare biologically interesting xanthones and thioxanthones. This chemistry presumably proceeds by a tandem intermolecular nucleophilic coupling and subsequent intramolecular electrophilic cyclization.

Concise synthesis of xanthones by the tandem etherification—Acylation of diaryliodonium salts with salicylates

An efficient synthetic method for multi-substituted xanthones was developed. The reaction of diaryliodonium salts and salicylates was employed for the preparation of the xanthones. This method proceeded through an intermolecular etherification-acylation t

Decarbonylative Methylation of Aromatic Esters by a Nickel Catalyst

A Ni-catalyzed decarbonylative methylation of aromatic esters was achieved using methylaluminums as methylating agents. Dimethylaluminum chlorides uniquely worked as the methyl source. Because of the Lewis acidity of aluminum reagents, less reactive alkyl esters could also undergo the present methylation. By controlling the Lewis acidity of aluminum reagents, a chemoselective decarbonylative cross-coupling between alkyl esters and phenyl esters was successful.