219858-15-8

Basic information

• Product Name: (E)-5-phenyl-2-nitropent-4-enoic acid methyl ester
• Synonyms: (E)-5-phenyl-2-nitropent-4-enoic acid methyl ester
• CAS NO: 219858-15-8
• Molecular Weight: 235.24
• Mol File: 219858-15-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (E)-5-phenyl-2-nitropent-4-enoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-5-phenyl-2-nitropent-4-enoic acid methyl ester(219858-15-8)
• EPA Substance Registry System: (E)-5-phenyl-2-nitropent-4-enoic acid methyl ester(219858-15-8)

Safety Data

• Hazardous Substances Data: 219858-15-8(Hazardous Substances Data)

Upstream product

• 2483-57-0 methyl 2-nitroacetate 
• 21040-45-9 Cinnamyl acetate 
• 300-57-2 allylbenzene 

Downstream Products

• 1073426-38-6 (+)-(S,E)-methyl 2-nitro-2-((S)-2-nitro-1-phenylethyl)-5-phenylpent-4-enoate 
• 103618-97-9 methyl 2-amino-5-phenyl-(RS)-(E)-4-pentenoate 

Relevant articles and documents

The Effect of Hydrogen Bonding on Allylic Alkylation and Isomerization Reactions in Ionic Liquids

Neutral allylic alkylation reactions, in which a base is generated in situ and which hence require no external bases, can significantly be retarded when carried out in the ionic liquid 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim][BF4]). Evidence suggests that the base or base precursor enters into hydrogen bonding with the imidazolium cation and is thus made less readily available for deprotonation of pre-nucleophiles. However, the reaction proceeds well in the presence of stronger bases that are capable of deprotonation. Whilst the phenomenon of hydrogen bonding in ionic liquids can be detrimental to reactions such as allylic alkylation, it can be exploited to suppress unwanted allylic isomerization.

Catalytic intermolecular allylic C-H alkylation

The first electrophilic Pd(II)-catalyzed allylic C-H alkylation is reported, providing a novel method for formation of sp3-sp3 C-C bonds directly from C-H bonds. A wide range of aromatic and heteroaromatic linear (E)-α-nitro-arylpent