220446-69-5

Basic information

• Product Name: ethyl (5-phenyl-1H-pyrrol-2-yl)acetate
• Synonyms: ethyl (5-phenyl-1H-pyrrol-2-yl)acetate
• CAS NO: 220446-69-5
• Molecular Weight: 229.279
• Mol File: 220446-69-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: ethyl (5-phenyl-1H-pyrrol-2-yl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (5-phenyl-1H-pyrrol-2-yl)acetate(220446-69-5)
• EPA Substance Registry System: ethyl (5-phenyl-1H-pyrrol-2-yl)acetate(220446-69-5)

Safety Data

• Hazardous Substances Data: 220446-69-5(Hazardous Substances Data)

Upstream product

• 3042-22-6 2-phenyl-1H-pyrrole 
• 1031223-78-5 C₁₈H₁₀F₅NO₂ 
• 64-17-5 ethanol 
• 201230-82-2 carbon monoxide 
• 271585-83-2 (+/-)-ethyl 6-(N-tert-butoxycarbonyl)amino-3-ethoxy-6-phenylhexa-2,4-dienoate 
• 140196-38-9 1,1-dimethyl (2-oxo-1-phenylethyl)carbamate 
• 145822-68-0 (E)-[2-ethoxy-3-(ethoxycarbonyl)-2-propenylidene]triphenylphosphorane 
• 271585-91-2 ethyl 1-(N-tert-butoxycarbonyl)-5-phenyl-2-pyrrolylacetate 

Downstream Products

• 5449-90-1 (5-phenyl-pyrrol-2-yl)-acetic acid 

Relevant articles and documents

Synthesis of 5-phenyl 2-functionalized pyrroles by amino Heck and Tandem amino Heck carbonylation reactions

2-Methyl-, 2-(methoxycarbonyl)methyl-, and 2,2-[(ethoxycarbonyl) (methoxycarbonyl)]methyl-5-phenylpyrroles are prepared from the corresponding 3-butynyl and 4-(methoxycarbonyl)-3-butynyl phenyl ketone O-pentafluorobenzoyl oximes by amino Heck cyclization

Synthesis of pyrrole derivatives by palladium-catalyzed cyclization of γ,δ-unsaturated ketone o-pentafluorobenzoyloximes

Various pyrrole derivatives are synthesized from γ,δ-unsaturated ketone O-pentafluorobenzoyloximes by treatment with catalytic amounts of Pd(PPh3)4 and triethylamine via alkylideneaminopalladium(II) intermediates generated by oxidative addition of the oximes to the Pd(0) complex.

Synthesis of pyrrole derivatives by the heck-type cyclization of γ,δ-unsaturated ketone O-pentafluorobenzoyloximes

Substituted pyrroles are synthesized from γδ-unsaturated ketone O-pentafluorobenzoyloximes by the intramolecular Heck-type amination of the olefinic moiety catalyzed by Pd(PPh3)4.