220556-53-6Relevant articles and documents
Synthesis and biological evaluation of 14-alkoxymorphinans. 16.1 14-0-alkyl derivatives of the μ opioid receptor antagonist cyprodime
Schmidhammer, Helmut,Krassnig, Roland,Greiner, Elisabeth,Traynor, John R.
, p. 489 - 497 (2007/10/03)
The 14-O-benzyl derivatives of cyprodime and 3-hydroxycyprodime (compounds (5) and (6), respectively) were synthesized in several steps from 3-desoxynaltrexone (2a) and naltrexone (2), respectively. In the mouse vas deferens preparation it was found that