22131-40-4

Basic information

• Product Name: 3-({[(2,5-dioxo-1-phenylimidazolidin-4-yl)methyl]sulfanyl}methyl)-5-phenylimidazolidine-2,4-dione
• CAS NO: 22131-40-4
• Molecular Formula: C₂₀H₁₈N₄O₄S
• Molecular Weight: 410.4463
• Mol File: 22131-40-4.mol
• Article Data: 1

Chemical Properties

• Density: 1.398g/cm³
• Refractive Index: 1.643
• CAS DataBase Reference: 3-({[(2,5-dioxo-1-phenylimidazolidin-4-yl)methyl]sulfanyl}methyl)-5-phenylimidazolidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-({[(2,5-dioxo-1-phenylimidazolidin-4-yl)methyl]sulfanyl}methyl)-5-phenylimidazolidine-2,4-dione(22131-40-4)
• EPA Substance Registry System: 3-({[(2,5-dioxo-1-phenylimidazolidin-4-yl)methyl]sulfanyl}methyl)-5-phenylimidazolidine-2,4-dione(22131-40-4)

Safety Data

• Hazardous Substances Data: 22131-40-4(Hazardous Substances Data)

Upstream product

• 1345332-84-4 C₂₈H₃₈N₄O₆S₂ 
• 103-71-9 phenyl isocyanate 
• 13059-63-7 L-cystine dihydrochloride 

Relevant articles and documents

Chelate oxorhenium to assemble new integrin antagonists

Assembly of independent chemical modules through oxorhenium coordination by a NS2 + S chelation motif was applied to the synthesis of RGD (Arg-Gly-Asp) analogs. Modules were assembled through oxorhenium chelation to give a series of 18 metal complexes in good yields and satisfactory purities. Screening of these oxorhenium coordinates as antagonists of integrins αVβ3, αIIbβ3 and αVβ5 led to the identification of 3 bioactive compounds that exhibit submicromolar affinities for the 3 integrins. Preliminary studies showed that the corresponding oxotechnetium complexes are stable in mice plasma and therefore could be proposed for the molecular imaging of pathologies that overexpress integrins αVβ3 and αVβ5.