2215-76-1Relevant articles and documents
Bis-Benzyl-Tetrahydroisoquinoline Derivatives As Therapeutics For Filovirus
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Paragraph 0058; 0059, (2019/09/20)
Bis-benzyl-tetrahydroisoquinoline analogs that are derivatives of the cyclic products tetrandrine (TETN) and cepharanthine (CEPH). The analogs indicate activity against filovirus infections, including the type species Marburg virus (MARV) and Ebola virus (EBOV).
Styrene-based compound and preparation method and application thereof
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, (2018/07/15)
The invention discloses a styrene-based compound, which is at least a 5-(4-(4-(3,5-dyhydroxystyryl)phenoxyl)styryl)-1,3-benzenediol compound of the following structural formula. The invention also discloses a preparation method and application of the 5-(4-(4-(3,5-dyhydroxystyryl)phenoxyl)styryl)-1,3-benzenediol compound of the structural formula. The 5-(4-(4-(3,5-dyhydroxystyryl)phenoxyl)styryl)-1,3-benzenediol compound disclosed by the invention is used for inhibiting the abnormal growth of B-cells by lowering AKT/mTOR signal conduction. The formula is shown in the specification.
Highly efficient heterogeneous copper-catalysed O-arylation of phenols by nitroarenes leading to diaryl ethers
Du, Yingying,Yao, Fang,Tuo, Yuxin,Cai, Mingzhong
, p. 725 - 729 (2018/01/08)
The heterogeneous O-arylation of phenols by nitroarenes was achieved in DMF at 100 °C by using an MCM-41-immobilised bidentate nitrogen copper(II) complex [MCM-41-2N-Cu(OAc)2] as catalyst, yielding a variety of unsymmetrical diaryl ethers in good to excellent yields. This heterogeneous copper catalyst can be easily prepared by a simple procedure from commercially readily available and inexpensive reagents, recovered by filtration of the reaction solution and recycled at least seven times without significant loss of activity.