22318-80-5

Basic information

• Product Name: 3,3',4,5'-tetrahydroxybibenzyl
• Synonyms: 3,3',4,5'-tetrahydroxybibenzyl;4-[2-(3,5-Dihydroxyphenyl)ethyl]-1,2-benzenediol;5-[2-(3,4-Dihydroxyphenyl)ethyl]-1,3-benzenediol;Dihydropiceatannol
• CAS NO: 22318-80-5
• Molecular Formula: C₁₄H₁₄O₄
• Molecular Weight: 246.26
• Mol File: 22318-80-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 482.9°Cat760mmHg
• Flash Point: 238.2°C
• Appearance: /
• Density: 1.393g/cm³
• Vapor Pressure: 5.98E-10mmHg at 25°C
• Refractive Index: 1.693
• PKA: 9.49±0.10(Predicted)
• CAS DataBase Reference: 3,3',4,5'-tetrahydroxybibenzyl(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3',4,5'-tetrahydroxybibenzyl(22318-80-5)
• EPA Substance Registry System: 3,3',4,5'-tetrahydroxybibenzyl(22318-80-5)

Safety Data

• Hazardous Substances Data: 22318-80-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H14O4/c15-11-5-10(6-12(16)8-11)2-1-9-3-4-13(17)14(18)7-9/h3-8,15-18H,1-2H2

Upstream product

• 10083-24-6 trans-piceatannol 
• 62502-05-0 3'-β-D-Glucopyranosyloxy-3,4,5'-trihydroxy-1,2-diphenylethane 
• 4339-71-3 piceatannol 
• 22268-21-9 3,4,3',5'-Tetraacetoxy-dibenzyl 
• 20578-93-2 3,4,3',5'-tetraacetoxy-stilbene 
• 24131-30-4 (3,5-dimethoxybenzyl)triphenylphosphonium bromide 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 20767-18-4 cis-trans-3,3',4',5-tetramethoxystilbene 
• 22318-87-2 3,5,4',5'-tetramethoxydihydrostilbene 
• 139-85-5 3,4-dihydroxybenzaldehyde 

Relevant articles and documents

Biologically active constituents of Melaleuca leucadendron: Inhibitors of induced histamine release from rat mast cells

Chloroform and methanol extracts of the fruits of Melaleuca leucadendron strongly inhibited histamine release from rat mast cells induced by compound 48/80 or concanavalin A. Ursolic acid, a triterpene, was the most active compound contained in the chloro

Prevention of Marine Biofouling Using the Natural Allelopathic Compound Batatasin-III and Synthetic Analogues

The current study reports the first comprehensive evaluation of a class of allelopathic terrestrial natural products as antifoulants in a marine setting. To investigate the antifouling potential of the natural dihydrostilbene scaffold, a library of 22 syn

Antioxidant constituents from rhubarb: Structural requirements of stilbenes for the activity and structures of two new anthraquinone glucosides

The methanolic extracts from five kinds of rhubarb were found to show scavenging activity for DPPH radical and ·O2-. Two new anthraquinone glucosides were isolated from the rhizome of Rheum undulatum L. together with two anthraquinone glucosides, a naphthalene glucoside, and 10 stilbenes. In the screening test for radical scavenging activity of rhubarb constituents, stilbenes and a naphthalene glucoside showed activity, but anthraquinones and sennosides did not. In addition, most stilbenes inhibited lipid peroxidation of erythrocyte membrane by tert-butyl hydroperoxide. Detailed examination of the scavenging effect on various related compounds suggested the following structural requirements; 1) phenolic hydroxyl groups are essential to show the activity; 2) galloyl moiety enhances the activity; 3) glucoside moiety reduces the activity; 4) dihydrostilbene derivatives maintain the scavenging activity for the DPPH radical, but they show weak activity for ·O2-. In addition, several stilbenes with both the 3-hydroxyl and 4′-methoxyl groups inhibited xanthine oxidase.