223599-66-4Relevant articles and documents
Design and synthesis of reagents for phage display screening of dehalogenases
Pieters, Roland J.,Fennema, Marko,Kellogg, Richard M.,Janssen, Dick B.
, p. 161 - 166 (1999)
Bifunctional molecules containing both a biotin and a substrate unit have been designed and synthesized for phage display screening of mutant libraries of haloalkane enzymes. The molecules were assembled using a convergent modular synthetic strategy. One molecule was synthesized to evaluate the concept of covalent capture and a second for screening of phage libraries for enantioselectivity.