22547-51-9

Basic information

• Product Name: N,4-dimethylbenzenesulfonohydrazide
• CAS NO: 22547-51-9
• Molecular Formula: C₈H₁₂N₂O₂S
• Molecular Weight: 200.2581
• Mol File: 22547-51-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 336.4°C at 760 mmHg
• Flash Point: 157.2°C
• Density: 1.264g/cm³
• Vapor Pressure: 0.000113mmHg at 25°C
• Refractive Index: 1.574
• CAS DataBase Reference: N,4-dimethylbenzenesulfonohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: N,4-dimethylbenzenesulfonohydrazide(22547-51-9)
• EPA Substance Registry System: N,4-dimethylbenzenesulfonohydrazide(22547-51-9)

Safety Data

• Hazardous Substances Data: 22547-51-9(Hazardous Substances Data)

Upstream product

• 104-15-4 toluene-4-sulfonic acid 
• 60-34-4 methylhydrazine 
• 640-61-9 N-methyl-p-toluenesulfonylamide 
• 74-88-4 methyl iodide 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 62655-41-8 Ethyliden-N-methyl-N-tosylhydrazon 
• 67406-87-5 Isopropyliden-N-methyl-N-tosylhydrazon 
• 102396-50-9 2-(ethylsulfonyl)-1-methyl-1-(4-tolylsulfonyl)hydrazine 
• 102396-54-3 2-(diphenylphosphinyl)-1-methyl-1-(4-tolylsulfonyl)hydrazine 
• 102235-38-1 2-Methoxycarbonylsulfenyl-1-methyl-1-(4-methylbenzenesulfonyl)hydrazine 
• 413582-57-7 salicylaldehyde-N-methyl p-toluenesulfonylhydrazone 
• 1616508-38-3 C₃₀H₃₀N₄O₆PdS₂ 
• 98394-34-4 2-(α-tolylsulfonyl)-1-methyl-1-(4-tolylsulfonyl)hydrazine 
• 102396-55-4 2-(diphenoxyphosphinyl)-1-methyl-1-(4-tolylsulfonyl)hydrazine 
• 98394-30-0 N'-(p-methoxybenzenesulfonyl)-N-methyl-N-(p-toluenesulfonyl)hydrazine 
• 98394-29-7 N'-benzenesulfonyl-N-methyl-N-(p-toluenesulfonyl)hydrazine 
• 98394-31-1 N'-(p-chlorobenzenesulfonyl)-N-methyl-N-(p-toluenesulfonyl)hydrazine 
• 102396-49-6 2-(methylsulfonyl)-1-methyl-1-(4-tolylsulfonyl)hydrazine 
• 102396-56-5 1-methyl-2-<(2-nitrophenyl)sulfenyl>-1-(4-tolylsulfonyl)hydrazine 

Relevant articles and documents

Synthesis, characterization, computational studies, antimicrobial activities and carbonic anhydrase inhibitor effects of 2-hydroxy acetophenone-N-methyl p-toluenesulfonylhydrazone and its Co(II), Pd(II), Pt(II) complexes

2-Hydroxyacetophenone-N-methyl p-toluenesulfonylhydrazone (afptsmh) derived from p-toluenesulfonicacid-1-methylhydrazide (ptsmh) and its Co(II), Pd(II), Pt(II) complexes were synthesized for the first time. Synthesized compounds were characterized by spec

Synthesis, characterization, antimicrobial activity and carbonic anhydrase enzyme inhibitor effects of salicilaldehyde-N-methyl p-toluenesulfonylhydrazone and its Palladium(II), Cobalt(II) complexes

We report the synthesis of the ligand, salicilaldehyde-N-methyl p-toluenesulfonylhydrazone (salptsmh) derived from p-toluenesulfonicacid-1- methylhydrazide (ptsmh) and its Pd(II) and Co(II) metal complexes were synthesized for the first time. The structure of the ligand and their complexes were investigated using elemental analysis, magnetic susceptibility, molar conductance and spectral (IR, NMR and LC-MS) measurements. Salptsmh has also been characterized by single crystal X-ray diffraction. 1H and 13C shielding tensors for crystal structure were calculated with GIAO/DFT/B3LYP/6-311++G(d,p) methods in CDCl3. The complexes were found to have general composition [ML2]. The results of elemental analysis showed 1:2 (metal/ligand) stoichiometry for all the complex. Magnetic and spectral data indicate a square planar geometry for Pd(II) complex and a distorted tetrahedral geometry for Co(II) complexes. The ligand and its metal chelates have been screened for their antimicrobial activities using the disk diffusion method against the selected Gram positive bacteria: Bacillus subtilis, Bacillus cereus, Staphylococcus aureus, Enterococcus faecalis, Gram negative bacteria: Eschericha coli, Pseudomonas aeruginosa, Klebsiella pneumonia. The inhibition activities of these compounds on carbonic anhydrase II (CA II) and carbonic anhydrase I (CA I) have been investigated by comparing IC50 and Ki values and it has been found that Pd(II) complex have more enzyme inhibition efficiency than salptsmh and Co(II) complex.

On the Mechanism of Sodium Cyanoborohydride Reduction of Tosylhydrazones

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