22582-52-1 Usage
General Description
1-(2-methyl-1H-indol-3-yl)ethanone, also known as 2-Methyl-1-(3-indolyl)ethanone, is a chemical compound with the molecular formula C11H11NO. It is a ketone derivative and contains an indole ring, which is a heterocyclic aromatic ring structure. 1-(2-methyl-1H-indol-3-yl)ethanone is commonly used in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It may also have potential applications in the field of medicinal chemistry for its pharmacological properties. Its structural features make it a versatile building block for the synthesis of diverse molecules for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 22582-52-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,5,8 and 2 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 22582-52:
(7*2)+(6*2)+(5*5)+(4*8)+(3*2)+(2*5)+(1*2)=101
101 % 10 = 1
So 22582-52-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H11NO/c1-7-11(8(2)13)9-5-3-4-6-10(9)12-7/h3-6,12H,1-2H3
22582-52-1Relevant articles and documents
Intermolecular dearomative C2-arylation of N-Ac indoles activated by FeCl3
Nandi, Raj Kumar,Ratsch, Friederike,Beaud, Rodolphe,Guillot, Régis,Kouklovsky, Cyrille,Vincent, Guillaume
, p. 5328 - 5331 (2016/04/26)
We report the FeCl3-mediated direct addition of electron-rich arenes to the C2-position of electrophilic N-Ac indoles under mild conditions (room temperature, air). No functional group is required on the arene nucleophile: one of its C-H bonds is added to the C2=C3 double bond of the indole nucleus in a Friedel-Crafts-type reaction. This dearomatisation process delivered a broad range of C2-arylated indolines.