226712-66-9

Basic information

• Product Name: 3'-bromo-2-methylstilbene
• Synonyms: 3'-bromo-2-methylstilbene
• CAS NO: 226712-66-9
• Molecular Weight: 273.172
• Mol File: 226712-66-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3'-bromo-2-methylstilbene(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-bromo-2-methylstilbene(226712-66-9)
• EPA Substance Registry System: 3'-bromo-2-methylstilbene(226712-66-9)

Safety Data

• Hazardous Substances Data: 226712-66-9(Hazardous Substances Data)

Upstream product

• 615-37-2 ortho-methylphenyl iodide 
• 2039-86-3 3-bromostyrene 
• 52457-01-9 3-Methylcyclohexa-1,4-diene-3-carboxylic acid 

Relevant articles and documents

Synthesis of Highly Substituted Arenes via Cyclohexadiene-Alkene C-H Cross Coupling and Aromatization

The development of a cross-coupling method for the regioselective β-alkenylation of 2,5-cyclohexadiene carboxylic acid derivatives to form ortho-alkenylarenes through in situ decarboxylation and aromatization is described. The carboxylic acid functionality is used as a traceless directing group for efficient and mild β-alkenylation. The modular sequence comprises a reductive Birch α-alkylation, ionic ?-alkylation followed by a Pd-catalyzed decarboxylative β-alkenylation with subsequent aromatization resulting in an overall three-fold ipso-para-ortho functionalization of readily accessed benzoic acid derivatives. Efficient synthesis of various alkyl-alkenylarenes under mild conditions in moderate to excellent yields is presented.