22717-95-9Relevant articles and documents
Selective Borylation of [4]Helicene
Ne?as, David,Kaiser, Reinhard P.,Ul?, Jan
, p. 5647 - 5652 (2016/12/14)
The Ir-catalyzed borylation of [4]helicene under different reaction conditions was studied for the first time. The results indicate that monoborylation proceeds to give a mixture of 2- and 3-borylated products in good yields (up to 74 % isolated yield). It was possible to shift the selectivity in favor of the 3-borylated product by using sterically demanding ligands. The monoborylated [4]helicenes were further arylated by using a Suzuki–Miyaura cross-coupling or oxidized to the corresponding phenols in very good yields.
Intramolecular gold(III) catalysed Diels-Alder reaction of 1-(2-furyl)-hex-1-en-5-yn-3-ol derivatives: A short and generalised route for the synthesis of hydroxyphenanthrene derivatives
Samanta, Khokan,Kar, Gandhi K.,Sarkar, Achintya K.
, p. 1376 - 1379 (2012/04/04)
Gold(III) catalysed intramolecular Diels-Alder reaction of various 1-(2-furyl)-hex-1-en-5-yn-3-ol derivatives has been studied to synthesise hydroxyphenanthrenes and other polynuclear aromatic hydroxyl compounds. The required precursors were synthesised by indium mediated propargylation of suitable β-furyl-α,β-unsaturated aldehydes.
An Efficient Synthesis of the Highly Tumorigenic anti-Diol Epoxide Derivative of Benzophenanthrene
Pataki, John,Raddo, Pasquale Di,Harvey, Ronald G.
, p. 840 - 844 (2007/10/02)
Synthesis of the potent tumorigen trans-3,4-dihydroxy-anti-1,2,3,4-tetrahydrobenzophenanthrene (1) in relatively few steps and superior overall yield is described.The method entails synthesis of the key intermediate 3-hydroxybenzophenanthrene (7b) v
