2304-96-3 Usage
Description
N-Benzyloxycarbonyl-L-asparagine, also known as Nα-Cbz-L-asparagine, is an N-Cbz-protected form of L-Asparagine (A790005). L-Asparagine is an amino acid that was first isolated by Robiquet and Vauquelin from asparagus juice, which is a high source of L-asparagine. It is commonly found in proteins and serves as a foundation for certain cancer therapies, as specific cancerous cells rely on L-asparagine for their growth. N-Benzyloxycarbonyl-L-asparagine is a white to light yellow crystalline powder and is used in various applications across different industries.
Uses
Used in Pharmaceutical Industry:
N-Benzyloxycarbonyl-L-asparagine is used as an intermediate in the synthesis of pharmaceutical compounds for cancer treatment. Its role is to provide a protected form of L-asparagine, which can be incorporated into drugs targeting cancer cells that require L-asparagine for their growth.
Used in Research and Development:
In the field of research and development, N-Benzyloxycarbonyl-L-asparagine is utilized as a reagent for the study of protein synthesis and the development of novel cancer therapies. Its protected structure allows for the exploration of new drug candidates and the investigation of L-asparagine's role in cancer cell growth.
Used in Chemical Synthesis:
N-Benzyloxycarbonyl-L-asparagine is employed as a building block in the chemical synthesis of various compounds, including those with potential applications in the pharmaceutical, agrochemical, and material science industries. Its unique structure and reactivity make it a valuable component in the development of new molecules with specific properties and functions.
Check Digit Verification of cas no
The CAS Registry Mumber 2304-96-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,3,0 and 4 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 2304-96:
(6*2)+(5*3)+(4*0)+(3*4)+(2*9)+(1*6)=63
63 % 10 = 3
So 2304-96-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H14N2O5/c13-10(15)6-9(11(16)17)14-12(18)19-7-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H2,13,15)(H,14,18)(H,16,17)/t9-/m1/s1
2304-96-3Relevant articles and documents
PYRROLOBENZODIAZEPINE DIMER PRECURSOR AND LIGAND-LINKER CONJUGATE COMPOUND THEREOF
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Paragraph 0251; 0252, (2020/02/18)
The present invention relates to a pyrrolobenzodiazepine dimer prodrug and a ligand-linker conjugate compound thereof, a composition containing these, and therapeutic use thereof particularly as an anticancer drug. The stability of the compounds themselves and the stability thereof in plasma are excellent and the compounds are advantageous in terms of manifestation of toxicity, and thus the compounds are industrially useful in that it is possible to target proliferative diseases such as cancer, to perform a specific treatment, to maximize the drug efficacy, and to minimize the occurrence of side effects.
Phosphate bioisostere containing amphiphiles: A novel class of squaramide-based lipids
Saha, Abhishek,Panda, Subhankar,Paul, Saurav,Manna, Debasis
supporting information, p. 9438 - 9441 (2016/07/29)
We describe a novel class of amphiphiles with squaramide moiety as a phosphate bioisostere. Most synthesized squaramide-based amphiphiles have the favorable physicochemical properties of lipids, such as: formation of stable liposomes or giant unilamellar vesicles in aqueous solution, high phase-transition temperature, low vesicle leakage and phospholipase resistance properties.
Solution phase synthetic approach to fellutamide B
Yadav, Jhillu Singh,Dachavaram, Soma Shekar,Grée, René,Das, Saibal
supporting information, p. 3999 - 4001 (2015/06/08)
Abstract A convenient solution phase approach for the synthesis of fellutamide B with efficient purification techniques has been demonstrated on the molecule for the first time. The strategy involves the use of natural amino acids as starting materials and classical peptide coupling reactions. The synthesis has been achieved in 10 steps with overall yield of 26.7% making the synthesis facile.